| Gene Symbol |
TSSK1B
|
| Entrez Gene |
83942
|
| Alt Symbol |
FKSG81, SPOGA4, STK22D, TSK1, TSSK1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
testis-specific serine kinase 1B
|
| Other Description |
TSK-1|TSSK-1|serine/threonine kinase 22D (spermiogenesis associated)|serine/threonine kinase FKSG81|serine/threonine-protein kinase 22A|spermiogenesis associated 4|testis-specific kinase 1|testis-specific serine kinase 1|testis-specific serine/threonine-protein kinase 1
|
| Swissprots |
Q9BXA7 B2R8D9
|
| Accessions |
BAF41973 CBH19487 CBH30711 EAW48983 Q9BXA7 AF348076 AAK29413 AK122904 BAG53792 AK313332 BAG36136 AY028964 AAK27734 BC022515 AAH22515 DB025324 DB527624 DQ893648 ABM84574 DQ895603 ABM86529 NM_032028 NP_114417
|
| Function |
Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates 'Ser-288' of TSKS. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body. {ECO:0000269|PubMed:15733851, ECO:0000269|PubMed:19530700}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250}. Cell projection, cilium, flagellum {ECO:0000250}. Note=In spermatozoa, present in the sperm head and in the flagellum. {ECO:0000250}.
|
| Tissue Specificity |
Testis-specific. Present in sperm (at protein level). {ECO:0000269|PubMed:15044604, ECO:0000269|PubMed:20729278}.
|