Sclt1

Gene Symbol Sclt1
Entrez Gene 266809
Alt Symbol CAP-1A, Sap1
Species Rat
Gene Type protein-coding
Description sodium channel and clathrin linker 1
Other Description clathrin-associated protein 1A|sodium channel Nav1.8-binding protein|sodium channel associated protein 1|sodium channel-associated protein 1
Swissprots Q8CJ98 Q8CJ84 Q8CJ83 Q8CJ99
Accessions EDM01353 EDM01354 EDM01355 EDM01356 EDM01357 Q8CJ99 AF421190 AAN32724 AF421191 AAN32725 AF427094 AAN63528 AF427095 AAN63529 XM_006232296 XP_006232358 XM_008760906 XP_008759128 NM_153740 NP_714962
Function Adapter protein that links SCN10A to clathrin. Regulates SCN10A channel activity, possibly by promoting channel internalization. {ECO:0000269|PubMed:15797711}.
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250}. Note=Localizes to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane. {ECO:0000250}.
Tissue Specificity Detected in small neurons in dorsal root ganglia. Detected in C-type fibers of sciatic nerve (at protein level). {ECO:0000269|PubMed:15797711}.

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