| Gene Symbol |
Sclt1
|
| Entrez Gene |
266809
|
| Alt Symbol |
CAP-1A, Sap1
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
sodium channel and clathrin linker 1
|
| Other Description |
clathrin-associated protein 1A|sodium channel Nav1.8-binding protein|sodium channel associated protein 1|sodium channel-associated protein 1
|
| Swissprots |
Q8CJ98 Q8CJ84 Q8CJ83 Q8CJ99
|
| Accessions |
EDM01353 EDM01354 EDM01355 EDM01356 EDM01357 Q8CJ99 AF421190 AAN32724 AF421191 AAN32725 AF427094 AAN63528 AF427095 AAN63529 XM_006232296 XP_006232358 XM_008760906 XP_008759128 NM_153740 NP_714962
|
| Function |
Adapter protein that links SCN10A to clathrin. Regulates SCN10A channel activity, possibly by promoting channel internalization. {ECO:0000269|PubMed:15797711}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250}. Note=Localizes to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane. {ECO:0000250}.
|
| Tissue Specificity |
Detected in small neurons in dorsal root ganglia. Detected in C-type fibers of sciatic nerve (at protein level). {ECO:0000269|PubMed:15797711}.
|