| Gene Symbol | DPM1 |
|---|---|
| Entrez Gene | 8813 |
| Alt Symbol | CDGIE, MPDS |
| Species | Human |
| Gene Type | protein-coding |
| Description | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit |
| Other Description | DPM synthase complex, catalytic subunit|DPM synthase subunit 1|MPD synthase subunit 1|dolichol monophosphate mannose synthase|dolichol-phosphate mannose synthase subunit 1|dolichol-phosphate mannosyltransferase subunit 1|dolichyl-phosphate beta-D-mannosyltransferase subunit 1|mannose-P-dolichol synthase subunit 1 |
| Swissprots | Q6IB78 O15157 O60762 Q96HK0 |
| Accessions | BAA25647 EAW75607 EAW75608 EAW75609 O60762 AF007875 AAC98797 AK289569 BAF82258 BC007073 AAH07073 BC008427 BC008466 AAH08466 BC016322 AAH16322 CR456926 CAG33207 D86198 BAA25646 HQ447146 ADQ31633 XM_005260600 XP_005260657 XM_005260601 XP_005260658 XM_011529093 XP_011527395 XM_011529094 XP_011527396 XR_244156 NM_003859 NP_003850 |
| Function | Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O- mannosylation of proteins; catalytic subunit of the dolichol- phosphate mannose (DPM) synthase complex. |
| Subcellular Location | Endoplasmic reticulum. |
| Top Pathways | N-Glycan biosynthesis |