| Gene Symbol |
CYTH4
|
| Entrez Gene |
27128
|
| Alt Symbol |
CYT4, DJ63G5.1, PSCD4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cytohesin 4
|
| Other Description |
PH, SEC7 and coiled-coil domain-containing protein 4|cytohesin-4|pleckstrin homology, Sec7 and coiled-coil domains 4|pleckstrin homology, Sec7 and coiled/coil domains 4
|
| Swissprots |
Q9UGT6 Q5R3F9 Q9UIA0
|
| Accessions |
EAW60154 EAW60155 EAW60156 Q9UIA0 AF075458 AAF15389 AF125349 AAF28896 AK002145 BAA92107 AK024428 BAB15718 AK304453 BAG65270 AK315052 BAG37529 BC017780 AAH17780 BC033693 BC041161 AAH41161 BP306826 CR456551 CAG30437 CU013151 CAK54582 CU013439 CAK54881 XM_011530147 XP_011528449 XM_011530148 XP_011528450 XR_430406 NM_013385 NP_037517
|
| Function |
Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP. {ECO:0000269|PubMed:10652308}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:17398095}; Peripheral membrane protein {ECO:0000269|PubMed:17398095}.
|
| Tissue Specificity |
Expressed predominantly in peripheral blood leukocytes. {ECO:0000269|PubMed:10652308}.
|
| Top Pathways |
Endocytosis
|