| Gene Symbol |
CRMP1
|
| Entrez Gene |
1400
|
| Alt Symbol |
CRMP-1, DPYSL1, DRP-1, DRP1, ULIP-3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
collapsin response mediator protein 1
|
| Other Description |
dihydropyrimidinase-like 1|dihydropyrimidinase-related protein 1|unc-33-like phosphoprotein 3
|
| Swissprots |
Q13024 A0EJG6 Q96TC8 Q4W5F1 Q14194
|
| Accessions |
AAY40959 CAR95648 CAR95649 CAT03387 CAT03388 EAW82403 EAW82404 EAW82405 EAW82406 EAW82407 Q14194 AK091696 AK094725 BAG52919 AK122754 BAG53708 AK127754 BAG54567 AK309379 BC000252 AAH00252 BC007613 AAH07613 BC007898 AAH07898 BC009987 BG701124 BT006806 AAP35452 D78012 BAA11190 DA064850 DA184461 DB498528 DQ206871 ABB22046 DQ892528 ABM83454 DQ895740 ABM86666 KJ534816 AHW56456 KJ534817 AHW56457 U17278 AAA93201 NM_001014809 NP_001014809 NM_001288661 NP_001275590 NM_001288662 NP_001275591 NM_001313 NP_001304
|
| Function |
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May participate in cytokinesis. {ECO:0000269|PubMed:11562390, ECO:0000269|PubMed:19799413}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:11562390}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:11562390}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:11562390}. Note=Associated with centrosomes and the mitotic spindle during metaphase.
|
| Tissue Specificity |
Brain.
|