Gene Symbol | ADAMTSL3 |
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Entrez Gene | 57188 |
Alt Symbol | ADAMTSL-3 |
Species | Human |
Gene Type | protein-coding |
Description | ADAMTS-like 3 |
Other Description | ADAMTS-like protein 3|a disintegrin-like and metalloprotease domain with thrombospondin type I motifs-like 3|punctin-2 |
Swissprots | P82987 Q9ULI7 A1A567 A1A566 |
Accessions | EAW62418 P82987 AB033059 BAA86547 AF237652 AAK15041 AK092324 AK308845 AL109723 AL109724 AW029535 BC128389 AAI28390 BC128390 AAI28391 BE646238 XM_011521821 XP_011520123 XM_011521822 XP_011520124 XM_011521823 XP_011520125 XM_011521824 XP_011520126 XM_011521825 XP_011520127 XR_931873 NM_001301110 NP_001288039 NM_207517 NP_997400 |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:14667842}. |
Tissue Specificity | Expressed in epithelial cells of the colon, fallopian tube, skin, breast, prostate, epididymis, liver, pancreatic islets and bile ducts, as well as by vascular endothelial cells, smooth muscle cells, fibroblasts, cortical and ganglionic neurons and cardiac myocytes. Also expressed by malignant epithelial cells in colon cancer, as well as breast, prostate, renal and skin tumors. Expression is significantly reduced in colon cancer compared to normal colon. {ECO:0000269|PubMed:14667842, ECO:0000269|PubMed:17597111}. |
Punctin-2 CRISPR/Cas9 KO Plasmid (h) - sc-408418 from Santa Cruz Biotechnology
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Punctin-2 HDR Plasmid (h) - sc-408418-HDR from Santa Cruz Biotechnology
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Punctin-2 Double Nickase Plasmid (h) - sc-408418-NIC from Santa Cruz Biotechnology
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Punctin-2 Double Nickase Plasmid (h2) - sc-408418-NIC-2 from Santa Cruz Biotechnology
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Punctin-2 CRISPR Activation Plasmid (h) - sc-408418-ACT from Santa Cruz Biotechnology
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Punctin-2 CRISPR Activation Plasmid (h2) - sc-408418-ACT-2 from Santa Cruz Biotechnology
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Punctin-2 Lentiviral Activation Particles (h) - sc-408418-LAC from Santa Cruz Biotechnology
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Punctin-2 Lentiviral Activation Particles (h2) - sc-408418-LAC-2 from Santa Cruz Biotechnology
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Punctin-2 siRNA (h) - sc-76299 from Santa Cruz Biotechnology
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Punctin-2 shRNA Plasmid (h) - sc-76299-SH from Santa Cruz Biotechnology
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Punctin-2 shRNA (h) Lentiviral Particles - sc-76299-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU082781 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2842 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2842 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR13216 from Sigma-Aldrich
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ADAMTSL3 siRNA (Human) - CRJ1387 from Cohesion Biosciences
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ADAMTSL3 - MBS8211675 from MyBioSource
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shRNA set against Human ADAMTSL3 (NM_207517.2) - SHH231970 from Creative biogene
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Human ADAMTSL3 siRNA - orb271888 from Biorbyt
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ADAMTSL3 shRNA Plasmid (Human) - CHJ1387 from Cohesion Biosciences
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ADAMTSL3 miRNA 3'UTR clone - MiUTR1H-00179 from Creative biogene
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