Gene Symbol | CBR3 |
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Entrez Gene | 874 |
Alt Symbol | HEL-S-25, SDR21C2, hCBR3 |
Species | Human |
Gene Type | protein-coding |
Description | carbonyl reductase 3 |
Other Description | NADPH-dependent carbonyl reductase 3|carbonyl reductase (NADPH) 3|carbonyl reductase [NADPH] 3|epididymis secretory protein Li 25|short chain dehydrogenase/reductase family 21C member 2|short chain dehydrogenase/reductase family 21C, member 2 |
Swissprots | O75828 Q6FHP2 |
Accessions | ABO43035 BAA34207 BAA89425 BAA95547 EAX09747 O75828 AB004850 AB004854 BAA33500 AB041012 BAD74062 AB124847 BAE45939 AJ000096 CAA03921 AK223429 BAD97149 BC002812 AAH02812 CR541709 CAG46510 FJ224313 ACI46005 JF432670 ADZ15887 XM_011529772 XP_011528074 NM_001236 NP_001227 |
Function | Has low NADPH-dependent oxidoreductase activity towards 4-benzoylpyridine and menadione (in vitro). {ECO:0000269|PubMed:18493841}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:18493841}. |
Tissue Specificity | Detected in ovary, pancreas, intestine, colon, kidney, brain, thymus, lung, heart, liver, spleen, leukocyte, prostate and testis. {ECO:0000269|PubMed:18493841}. |
Top Pathways | Arachidonic acid metabolism, Metabolism of xenobiotics by cytochrome P450 |
Carbonyl reductase 3 CRISPR/Cas9 KO Plasmid (h) - sc-406552 from Santa Cruz Biotechnology
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Carbonyl reductase 3 HDR Plasmid (h) - sc-406552-HDR from Santa Cruz Biotechnology
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Carbonyl reductase 3 Double Nickase Plasmid (h) - sc-406552-NIC from Santa Cruz Biotechnology
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Carbonyl reductase 3 Double Nickase Plasmid (h2) - sc-406552-NIC-2 from Santa Cruz Biotechnology
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Carbonyl reductase 3 CRISPR Activation Plasmid (h) - sc-406552-ACT from Santa Cruz Biotechnology
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Carbonyl reductase 3 CRISPR Activation Plasmid (h2) - sc-406552-ACT-2 from Santa Cruz Biotechnology
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Carbonyl reductase 3 Lentiviral Activation Particles (h) - sc-406552-LAC from Santa Cruz Biotechnology
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Carbonyl reductase 3 Lentiviral Activation Particles (h2) - sc-406552-LAC-2 from Santa Cruz Biotechnology
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Carbonyl reductase 3 siRNA (h) - sc-72793 from Santa Cruz Biotechnology
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Carbonyl reductase 3 shRNA Plasmid (h) - sc-72793-SH from Santa Cruz Biotechnology
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Carbonyl reductase 3 shRNA (h) Lentiviral Particles - sc-72793-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU155671 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5417 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5417 from Sigma-Aldrich
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CBR3 siRNA (Human) - CRH0617 from Cohesion Biosciences
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CBR3 RNAi - H00000874-R01 from Novus Biologicals
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CBR3 - MBS8220706 from MyBioSource
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Carbonyl reductase 3 CRISPR/Cas9 KO Plasmid (h2) - sc-406552-KO-2 from Santa Cruz Biotechnology
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Carbonyl reductase 3 HDR Plasmid (h2) - sc-406552-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human CBR3 (NM_001236.3) - SHH255421 from Creative biogene
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CBR3 shRNA Plasmid (Human) - CHH0617 from Cohesion Biosciences
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CBR3 miRNA 3'UTR clone - MiUTR1H-01707 from Creative biogene
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