| Gene Symbol | GPX5 |
|---|---|
| Entrez Gene | 2880 |
| Alt Symbol | HEL-S-75p |
| Species | Human |
| Gene Type | protein-coding |
| Description | glutathione peroxidase 5 |
| Other Description | EGLP|GPx-5|GSHPx-5|epididymal androgen-related protein|epididymal secretory glutathione peroxidase|epididymis secretory sperm binding protein Li 75p|epididymis-specific glutathione peroxidase-like protein |
| Swissprots | O75715 A1A4Y0 |
| Accessions | AAW56939 EAX03168 EAX03169 O75715 AJ005277 CAA06463 AK093099 BAG52653 BC111375 AAI11376 BC128159 AAI28160 BC128160 AAI28161 BX103177 DB336279 FJ460514 ACS44651 XM_011514527 XP_011512829 XM_011514528 XP_011512830 XM_011514529 XP_011512831 XM_011514530 XP_011512832 XM_011547233 XP_011545535 XM_011547234 XP_011545536 XM_011547235 XP_011545537 XM_011547236 XP_011545538 NM_001509 NP_001500 NM_003996 NP_003987 |
| Function | Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. |
| Subcellular Location | Secreted. |
| Tissue Specificity | Epididymis. |
| Top Pathways | Thyroid hormone synthesis, Glutathione metabolism, Arachidonic acid metabolism |