Gene Symbol | SRPR |
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Entrez Gene | 6734 |
Alt Symbol | DP, Sralpha |
Species | Human |
Gene Type | protein-coding |
Description | signal recognition particle receptor (docking protein) |
Other Description | DP-alpha|SR-alpha|SRP-alpha|docking protein alpha|signal recognition particle receptor subunit alpha |
Swissprots | B2R5Z8 E9PJS4 P08240 B4E0H3 Q9BVJ4 A6NIB3 |
Accessions | EAW67684 EAW67685 EAW67686 P08240 AI422194 AK130382 AK303379 BAG64435 AK312377 BAG35295 BC001162 AAH01162 BC008077 BC009110 AAH09110 BC013583 AAH13583 CR457025 CAG33306 DQ891476 ABM82402 DQ894664 ABM85590 X06272 CAA29608 NM_001177842 NP_001171313 NM_003139 NP_003130 |
Function | Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. |
Subcellular Location | Endoplasmic reticulum membrane; Peripheral membrane protein. Note=Thought to be anchored in the membrane through an interaction with SR-beta, which contains a bona fide transmembrane domain. |
Top Pathways | Protein export |
SR-α CRISPR/Cas9 KO Plasmid (h) - sc-417012 from Santa Cruz Biotechnology
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SR-α HDR Plasmid (h) - sc-417012-HDR from Santa Cruz Biotechnology
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SR-α Double Nickase Plasmid (h) - sc-417012-NIC from Santa Cruz Biotechnology
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SR-α Double Nickase Plasmid (h2) - sc-417012-NIC-2 from Santa Cruz Biotechnology
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SR-α CRISPR Activation Plasmid (h) - sc-417012-ACT from Santa Cruz Biotechnology
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SR-α CRISPR Activation Plasmid (h2) - sc-417012-ACT-2 from Santa Cruz Biotechnology
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SR-α Lentiviral Activation Particles (h) - sc-417012-LAC from Santa Cruz Biotechnology
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SR-α Lentiviral Activation Particles (h2) - sc-417012-LAC-2 from Santa Cruz Biotechnology
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SR-α siRNA (h) - sc-96514 from Santa Cruz Biotechnology
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SR-α shRNA Plasmid (h) - sc-96514-SH from Santa Cruz Biotechnology
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SR-α shRNA (h) Lentiviral Particles - sc-96514-V from Santa Cruz Biotechnology
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SRPR alpha RNAi - H00006734-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN20586 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20586 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07976 from Sigma-Aldrich
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SRPR siRNA (Human) - CRH4601 from Cohesion Biosciences
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SRPR - MBS829206 from MyBioSource
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shRNA set against Human SRPR (NM_003139.3) - SHH418024 from Creative biogene
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SRPR shRNA Plasmid (Human) - CHH4601 from Cohesion Biosciences
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SRPR miRNA 3'UTR clone - MiUTR3H-02098 from Creative biogene
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