Gene Symbol | SHMT2 |
---|---|
Entrez Gene | 6472 |
Alt Symbol | GLYA, HEL-S-51e, SHMT |
Species | Human |
Gene Type | protein-coding |
Description | serine hydroxymethyltransferase 2 (mitochondrial) |
Other Description | GLY A+|epididymis secretory sperm binding protein Li 51e|glycine auxotroph A, human complement for hamster|glycine hydroxymethyltransferase|serine aldolase|serine hydroxymethylase|serine hydroxymethyltransferase, mitochondrial|serine methylase|threonine aldolase |
Swissprots | E7EU43 P34897 O00740 E7EQ19 Q8N1A5 B7Z9F1 |
Accessions | AAA64572 CAA72999 CAY55993 EAW96993 EAW96994 EAW96995 EAW96996 EAW96997 EAW96998 EAW96999 EAW97000 EAW97001 P34897 AK055053 AK223555 BAD97275 AK295941 BAG58725 AK296183 BAG58915 AK297173 BAG59666 AK298231 BAG60500 AK301339 BAG62887 AK301443 BAG62969 AK303827 BAG64774 AK315916 BAH14287 BC008066 BC008711 BC011911 AAH11911 BC013677 AAH13677 BC025355 BC032584 AAH32584 BC044211 AAH44211 BC091501 AAH91501 BT006866 AAP35512 BX647711 CAI46021 BX648847 CN395976 DA052422 DC339924 DC386590 DQ891309 ABM82235 DQ894430 ABM85356 EU668344 ACF94497 L11932 AAA63258 XM_011538675 XP_011536977 XM_011538676 XP_011536978 XM_011538677 XP_011536979 XM_011538678 XP_011536980 NM_001166356 NP_001159828 NM_001166357 NP_001159829 NM_001166358 NP_001159830 NM_001166359 NP_001159831 NM_005412 NP_005403 NR_029415 NR_029416 NR_029417 NR_048562 |
Function | Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Interconversion of serine and glycine. Associates with mitochondrial DNA. {ECO:0000269|PubMed:21876188}. |
Subcellular Location | Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid. Mitochondrion inner membrane. |
Top Pathways | Glycine, serine and threonine metabolism, Glyoxylate and dicarboxylate metabolism, Cyanoamino acid metabolism, Biosynthesis of amino acids, Carbon metabolism |
Recombinant Human SHMT2 Protein - H00006472-Q01 from Novus Biologicals
|
||||||||||
Recombinant Human SHMT2 Protein - H00006472-P01 from Novus Biologicals
|
||||||||||
SHMT2 Protein Lysate (APL11045) - APL11045 from Aviva Systems Biology
|
||||||||||
SHMT2 Protein Lysate (APL11046) - APL11046 from Aviva Systems Biology
|
||||||||||
SHMT2 Protein Lysate (APL11047) - APL11047 from Aviva Systems Biology
|
||||||||||
SHMT2 Blocking Peptide - 33R-2550 from Fitzgerald
|
||||||||||
SHMT2 Blocking Peptide - 33R-2579 from Fitzgerald
|
||||||||||
SHMT2 / SHMT - H00006472-P01 from Acris Antibodies
|
||||||||||
SHMT2 / SHMT - H00006472-Q01-10 from Acris Antibodies
|
||||||||||
SHMT2 / SHMT - H00006472-Q01-25 from Acris Antibodies
|
||||||||||
SHMT2 fusion protein - Ag1584 from Proteintech Group
|
||||||||||
Recombinant Human SHMT2, His-tagged - SHMT2-31356TH from Creative Biomart
|
||||||||||
Recombinant Human SHMT2, GST-tagged - SHMT2-2662H from Creative Biomart
|
||||||||||
Recombinant Serine Hydroxymethyltransferase 2, Mitochondrial (SHMT2) - RPE217Hu01 from Uscn Life Science Inc.
|
||||||||||
Recombinant Human Serine hydroxymethyltransferase, mitochondrial(SHMT2) - CSB-YP021274HU CSB-EP021274HU CSB-BP021274HU CSB-MP021274HU from Cusabio
|
||||||||||
SHMT2 / SHMT (full length, N-term HIS tag) - TP760127 from Acris Antibodies
|
||||||||||
SHMT2 Recombinant Protein Antigen - NBP1-80755PEP from Novus Biologicals
|
||||||||||
SHMT2 Recombinant Protein Antigen - NBP1-80754PEP from Novus Biologicals
|
||||||||||
SHMT2 Protein Lysate - orb333622 from Biorbyt
|
||||||||||
SHMT2 Peptide, Human - M34GP14218H from Creative Peptides
|
||||||||||
SHMT2 Protein Lysate - orb333621 from Biorbyt
|
||||||||||
SHMT2 Protein Lysate - orb333620 from Biorbyt
|
||||||||||
SHMT2 Recombinant Protein (OPCD06964) - OPCD06964 from Aviva Systems Biology
|
||||||||||
Serine hydroxymethyltransferase, mitochondrial, Recombinant Protein - MBS1138365 from MyBioSource
|
||||||||||
Serine hydroxymethyltransferase, mitochondrial, Recombinant Protein - MBS1000700 from MyBioSource
|