| Gene Symbol | DLST |
|---|---|
| Entrez Gene | 1743 |
| Alt Symbol | DLTS |
| Species | Human |
| Gene Type | protein-coding |
| Description | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) |
| Other Description | E2K|OGDC-E2|dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial |
| Swissprots | Q9BQ32 P36957 E7ESY5 B7Z5W8 Q7LDY7 |
| Accessions | AAD30181 BAA05536 EAW81199 EAW81200 EAW81201 EAW81202 P36957 AA101667 AI087261 AK289414 BAF82103 AK299505 BAH13054 AK300396 BAH13277 AK316463 BAH14834 AL538322 AU133381 BC000302 AAH00302 BC001922 AAH01922 BC002735 BM682697 BM928746 BM929953 BU623022 BX248276 CAD62604 BX248764 CAD66571 BX248774 CAD66581 CN422511 CR456727 CAG33008 CX163292 D16373 BAA03871 D17297 BAA04130 DA995927 DC338747 HQ448281 ADQ32761 L37418 AAB59629 NM_001244883 NP_001231812 NM_001933 NP_001924 NR_033814 NR_045209 |
| Function | The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). |
| Subcellular Location | Mitochondrion. |
| Top Pathways | Citrate cycle (TCA cycle), Lysine degradation, Carbon metabolism |