Gene Symbol | ENGASE |
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Entrez Gene | 64772 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | endo-beta-N-acetylglucosaminidase |
Other Description | Di-N-acetylchitobiosyl beta-N-acetylglucosaminidase|Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase|cytosolic endo-beta-N-acetylglucosaminidase |
Swissprots | Q8TB86 Q9H6U4 Q659F0 Q8NFI3 |
Accessions | EAW89559 EAW89560 EAW89561 EAW89562 Q8NFI3 AF512564 AAM80487 AK025518 BAB15158 AK301115 BAG62712 AL110283 CAH56405 BC024213 AAH24213 BC042158 BC156537 AAI56538 XM_006722015 XP_006722078 XM_006722016 XP_006722079 XM_006722017 XP_006722080 XM_006722018 XP_006722081 XM_006722019 XP_006722082 XR_429918 XR_429919 XR_429920 XR_934534 XR_934535 XR_934536 NM_022759 NM_001042573 NP_001036038 |
Function | Endoglycosidase that releases N-glycans from glycoproteins by cleaving the beta-1,4-glycosidic bond in the N,N'-diacetylchitobiose core. Involved in the processing of free oligosaccharides in the cytosol. {ECO:0000269|PubMed:12114544}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000250}. |
Tissue Specificity | Widely expressed. Expressed at higher level in thymus and spleen. {ECO:0000269|PubMed:12114544}. |
Top Pathways | Other glycan degradation |
ENGase CRISPR/Cas9 KO Plasmid (h) - sc-413031 from Santa Cruz Biotechnology
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ENGase HDR Plasmid (h) - sc-413031-HDR from Santa Cruz Biotechnology
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ENGase Double Nickase Plasmid (h) - sc-413031-NIC from Santa Cruz Biotechnology
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ENGase Double Nickase Plasmid (h2) - sc-413031-NIC-2 from Santa Cruz Biotechnology
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ENGase CRISPR Activation Plasmid (h) - sc-413031-ACT from Santa Cruz Biotechnology
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ENGase CRISPR Activation Plasmid (h2) - sc-413031-ACT-2 from Santa Cruz Biotechnology
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ENGase Lentiviral Activation Particles (h) - sc-413031-LAC from Santa Cruz Biotechnology
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ENGase Lentiviral Activation Particles (h2) - sc-413031-LAC-2 from Santa Cruz Biotechnology
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ENGase siRNA (h) - sc-77375 from Santa Cruz Biotechnology
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ENGase shRNA Plasmid (h) - sc-77375-SH from Santa Cruz Biotechnology
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ENGase shRNA (h) Lentiviral Particles - sc-77375-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU088071 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7869 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7869 from Sigma-Aldrich
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ENGASE siRNA (Human) - CRJ2079 from Cohesion Biosciences
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ENGASE - MBS8200152 from MyBioSource
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shRNA set against Human ENGASE (NM_001042573.2) - SHH285781 from Creative biogene
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Human ENGASE siRNA - orb272580 from Biorbyt
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ENGASE shRNA Plasmid (Human) - CHJ2079 from Cohesion Biosciences
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