Gene Symbol |
LAMB3
|
Entrez Gene |
3914
|
Alt Symbol |
AI1A, BM600-125KDA, LAM5, LAMNB1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
laminin, beta 3
|
Other Description |
epiligrin subunit bata|kalinin B1 chain|kalinin subunit beta|kalinin-140kDa|laminin B1k chain|laminin S B3 chain|laminin subunit beta-3|laminin, beta 3 (nicein (125kD), kalinin (140kD), BM600 (125kD))|laminin-5 subunit beta|nicein subunit beta|nicein-125kDa
|
Swissprots |
Q9UJK4 Q14733 O14947 Q13751 Q9UJL1 D3DT88
|
Accessions |
AAC51352 EAW93448 EAW93449 Q13751 AK296851 BAG59417 AK309524 AL555685 AY035783 AAK61364 BC058922 BC075838 AAH75838 BP350980 BX345166 CN414822 D37766 BAA22263 EU831471 ACE87158 EU831558 ACE86477 L25541 AAA61834 XM_005273124 XP_005273181 NM_000228 NP_000219 NM_001017402 NP_001017402 NM_001127641 NP_001121113
|
Function |
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
|
Subcellular Location |
Secreted, extracellular space, extracellular matrix, basement membrane.
|
Tissue Specificity |
Found in the basement membranes (major component).
|
Top Pathways |
Focal adhesion, ECM-receptor interaction, Small cell lung cancer, Amoebiasis, Toxoplasmosis
|