Gene Symbol | NFE2L3 |
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Entrez Gene | 9603 |
Alt Symbol | NRF3 |
Species | Human |
Gene Type | protein-coding |
Description | nuclear factor, erythroid 2-like 3 |
Other Description | NF-E2-related factor 3|NFE2-related factor 3|nuclear factor (erythroid-derived 2)-like 3|nuclear factor erythroid 2-related factor 3|nuclear factor, erythroid derived 2, like 3|nuclear factor-erythroid 2 p45-related factor 3|nuclear factor-erythroid 2-related factor 3 |
Swissprots | Q86VR5 Q9Y4A8 Q6NUS0 Q9UQA4 Q86UJ4 Q7Z498 |
Accessions | AAF61415 AAP22344 EAL24236 EAW93833 Q9Y4A8 AA603252 AB010812 BAA76288 AF125534 AAF17228 AF133059 AAG43275 AF134891 AAF61404 BC008645 BC015336 AAH15336 BC035762 BC049219 AAH49219 BC056142 AAH56142 BC068455 AAH68455 BX396198 NM_004289 NP_004280 |
Function | Activates erythroid-specific, globin gene expression. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00978}. |
Tissue Specificity | Highly expressed in human placenta and also in B-cell and monocyte cell lines. Low expression in heart, brain, lung, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:10037736}. |
Nrf3 CRISPR/Cas9 KO Plasmid (h) - sc-404543 from Santa Cruz Biotechnology
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Nrf3 HDR Plasmid (h) - sc-404543-HDR from Santa Cruz Biotechnology
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Nrf3 Double Nickase Plasmid (h) - sc-404543-NIC from Santa Cruz Biotechnology
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Nrf3 Double Nickase Plasmid (h2) - sc-404543-NIC-2 from Santa Cruz Biotechnology
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Nrf3 CRISPR Activation Plasmid (h) - sc-404543-ACT from Santa Cruz Biotechnology
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Nrf3 CRISPR Activation Plasmid (h2) - sc-404543-ACT-2 from Santa Cruz Biotechnology
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Nrf3 Lentiviral Activation Particles (h) - sc-404543-LAC from Santa Cruz Biotechnology
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Nrf3 Lentiviral Activation Particles (h2) - sc-404543-LAC-2 from Santa Cruz Biotechnology
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Nrf3 siRNA (h) - sc-38107 from Santa Cruz Biotechnology
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Nrf3 shRNA Plasmid (h) - sc-38107-SH from Santa Cruz Biotechnology
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Nrf3 shRNA (h) Lentiviral Particles - sc-38107-V from Santa Cruz Biotechnology
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NRF3 RNAi - H00009603-R01 from Novus Biologicals
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MISSION® esiRNA - EHU109071 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15246 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15246 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04375 from Sigma-Aldrich
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NFE2L3 siRNA (Human) - CRH6389 from Cohesion Biosciences
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shRNA set against Human NFE2L3 (NM_004289.6) - SHH351800 from Creative biogene
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NFE2L3 shRNA Plasmid (Human) - CHH6389 from Cohesion Biosciences
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NFE2L3 miRNA 3'UTR clone - MiUTR3H-06583 from Creative biogene
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