Gene Symbol | CDS1 |
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Entrez Gene | 1040 |
Alt Symbol | CDS |
Species | Human |
Gene Type | protein-coding |
Description | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 |
Other Description | CDP-DAG synthase 1|CDP-DG synthase 1|CDP-DG synthetase 1|CDP-diacylglycerol synthase 1|CDP-diglyceride pyrophosphorylase 1|CDP-diglyceride synthase 1|CDP-diglyceride synthetase 1|CDS 1|CTP:phosphatidate cytidylyltransferase 1|phosphatidate cytidylyltransferase 1 |
Swissprots | B2RAL5 O00163 Q92903 |
Accessions | EAX05950 EAX05951 Q92903 AI673547 AK026697 AK314245 BAG36912 AU139278 BC074833 AAH74833 BC074881 AAH74881 BE504303 CA313675 DN915398 U60808 AAC51184 U65887 AAC50735 XM_005262687 XP_005262744 NM_001263 NP_001254 |
Function | Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol (PtdIns), phosphatidylglycerol, and cardiolipin. Overexpression may amplify cellular signaling responses from cytokines. May also play an important role in the signal transduction mechanism of retina and neural cells. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Cytoplasmic aspect of the endoplasmic reticulum. {ECO:0000250}. |
Tissue Specificity | Expressed in adult tissues such as placenta, brain, small intestine, ovary, testis and prostate. Highly expressed in fetal kidney, lung and brain. Lower level in fetal liver. |
Top Pathways | Glycerophospholipid metabolism, Phosphatidylinositol signaling system |
Anti-CDS1 antibody - ab84019 from Abcam
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Anti-CDS1 antibody - ab88121 from Abcam
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Anti-CDS1 Antibody (aa288-337) - LS-C102157 from LifeSpan Bioscience
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Anti-CDS1 Antibody (N-Terminus) - LS-C116288 from LifeSpan Bioscience
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Anti-CDS1 Antibody (clone 2D10) - LS-C196890 from LifeSpan Bioscience
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CDS1 Antibody (2D10) - H00001040-M01 from Novus Biologicals
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CDS1 Antibody - NBP1-85894 from Novus Biologicals
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CDS1 Antibody - NBP1-59495 from Novus Biologicals
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CDS1 Antibody - NBP1-33434 from Novus Biologicals
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Anti-CDS1 antibody produced in rabbit - HPA036187 from Sigma-Aldrich
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Anti-CDS1 antibody produced in rabbit - SAB2100392 from Sigma-Aldrich
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Monoclonal Anti-CDS1, (N-terminal) antibody produced in mouse - SAB1402148 from Sigma-Aldrich
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Anti-CDS1 antibody produced in rabbit - SAB2702068 from Sigma-Aldrich
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CDS1 antibody - N-terminal region (ARP45071_P050) - ARP45071_P050 from Aviva Systems Biology
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CDS1 antibody - middle region (ARP45073_P050) - ARP45073_P050 from Aviva Systems Biology
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CDS1 antibody [C1C3] - GTX112491 from GeneTex
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Chk2 (phospho Ser516) antibody - GTX50205 from GeneTex
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Chk2 (phospho Thr387) antibody - GTX79109 from GeneTex
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Chk2 antibody - GTX50698 from GeneTex
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CHEK2 antibody - 10R-6851 from Fitzgerald
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Chk2 antibody (Ser516) - 70R-37225 from Fitzgerald
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CDS1 antibody - 70R-8618 from Fitzgerald
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Chk2 antibody (Ser516) - 70R-36668 from Fitzgerald
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Chk2 antibody (Ser33) - 70R-37393 from Fitzgerald
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Anti -CDS1 - C2582 from USBiological Life Science
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