| Gene Symbol |
CSGALNACT2
|
| Entrez Gene |
55454
|
| Alt Symbol |
CHGN2, GALNACT-2, GALNACT2, PRO0082
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
chondroitin sulfate N-acetylgalactosaminyltransferase 2
|
| Other Description |
beta 4 GalNAcT-2|chondroitin beta1,4 N-acetylgalactosaminyltransferase 2
|
| Swissprots |
Q9P1I6 B3KWL7 Q6MZJ5 Q8N6G5 Q8TCH4 Q6MZP6
|
| Accessions |
EAW86586 EAW86587 Q8N6G5 AA721408 AB079252 BAC55935 AB090811 BAC55936 AF086458 AF116646 AAF71068 AK074474 BAB85092 AK125300 BAG54179 BC030268 AAH30268 BX102005 BX640967 CAE45982 BX641073 CAE46036 BX647369 DA674683 DB291068 DQ891469 ABM82395 DQ894653 ABM85579 XM_011539938 XP_011538240 XM_011539939 XP_011538241 XR_945783 NM_018590 NP_061060
|
| Function |
Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. {ECO:0000269|PubMed:12433924, ECO:0000269|PubMed:12446672}.
|
| Subcellular Location |
Golgi apparatus, Golgi stack membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:12433924, ECO:0000269|PubMed:12446672}.
|
| Top Pathways |
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
|
![Western Blot: CSGALNACT2 Overexpression Lysate (Adult Normal) [NBL1-09521] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CSGALNACT2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9607_CSGALNACT2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-09521-img0002.jpg)