| Gene Symbol |
GDI2
|
| Entrez Gene |
2665
|
| Alt Symbol |
HEL-S-46e, RABGDIB
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
GDP dissociation inhibitor 2
|
| Other Description |
GDI-2|epididymis secretory sperm binding protein Li 46e|guanosine diphosphate dissociation inhibitor 2|rab GDI beta|rab GDP dissociation inhibitor beta|rab GDP-dissociation inhibitor, beta
|
| Swissprots |
O43928 P50395 Q9UQM6 Q5SX88
|
| Accessions |
CAA73735 EAW86430 EAW86431 EAW86432 P50395 AB451295 BAG70109 AB451429 BAG70243 AF144713 AAD34588 AK094671 AK122841 BAG53755 AK297177 BAG59669 AK297554 BAG59947 AK309360 AK312485 BAG35388 BC005145 AAH05145 BC024168 AAH24168 BT006868 AAP35514 BX648038 CR457073 CAG33354 D13988 BAA03095 DA069966 DQ890573 ABM92190 DQ893733 ABM84659 EU794614 ACJ13668 Y13286 CAA73734 NM_001115156 NP_001108628 NM_001494 NP_001485
|
| Function |
Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:7543319}.
|
![Western Blot: GDI2 Overexpression Lysate (Adult Normal) [NBL1-11030] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GDI2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8308_GDI2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11030-img0002.jpg)