Gene Symbol | SLC32A1 |
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Entrez Gene | 140679 |
Alt Symbol | VGAT, VIAAT |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 32 (GABA vesicular transporter), member 1 |
Other Description | GABA and glycine transporter|hVIAAT|solute carrier family 32 member 1|vesicular GABA transporter|vesicular inhibitory amino acid transporter |
Swissprots | Q9H598 Q8N489 |
Accessions | EAW76012 Q9H598 AF064848 AK055051 BAB70846 AK091079 BAG52280 AY044836 AAK98782 BC036458 AAH36458 BC053582 AAH53582 BI488536 NM_080552 NP_542119 |
Function | Involved in the uptake of GABA and glycine into the synaptic vesicles. |
Subcellular Location | Cytoplasmic vesicle membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Tissue Specificity | Retina. Expressed throughout the horizontal cells or more specifically at the terminals. {ECO:0000269|PubMed:12115694}. |
Top Pathways | Synaptic vesicle cycle, GABAergic synapse, Morphine addiction, Nicotine addiction, Retrograde endocannabinoid signaling |
VGAT CRISPR/Cas9 KO Plasmid (h) - sc-401850 from Santa Cruz Biotechnology
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VGAT HDR Plasmid (h) - sc-401850-HDR from Santa Cruz Biotechnology
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VGAT Double Nickase Plasmid (h) - sc-401850-NIC from Santa Cruz Biotechnology
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VGAT Double Nickase Plasmid (h2) - sc-401850-NIC-2 from Santa Cruz Biotechnology
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VGAT CRISPR Activation Plasmid (h) - sc-401850-ACT from Santa Cruz Biotechnology
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VGAT CRISPR Activation Plasmid (h2) - sc-401850-ACT-2 from Santa Cruz Biotechnology
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VGAT Lentiviral Activation Particles (h) - sc-401850-LAC from Santa Cruz Biotechnology
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VGAT Lentiviral Activation Particles (h2) - sc-401850-LAC-2 from Santa Cruz Biotechnology
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VGAT siRNA (h) - sc-61782 from Santa Cruz Biotechnology
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VGAT shRNA Plasmid (h) - sc-61782-SH from Santa Cruz Biotechnology
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VGAT shRNA (h) Lentiviral Particles - sc-61782-V from Santa Cruz Biotechnology
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VIAAT/SLC32A1/VGAT RNAi - H00140679-R01 from Novus Biologicals
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MISSION® esiRNA - EHU142571 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19567 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19567 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06298 from Sigma-Aldrich
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SLC32A1 siRNA (Human) - CRJ5295 from Cohesion Biosciences
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SLC32A1 - MBS8204664 from MyBioSource
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shRNA set against Human SLC32A1 (NM_080552.2) - SHH410496 from Creative biogene
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shRNA set against Human SLC32A1(NM_080552.2) - SHL006652 from Creative biogene
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Human SLC32A1 siRNA - orb275796 from Biorbyt
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SLC32A1 shRNA Plasmid (Human) - CHJ5295 from Cohesion Biosciences
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SLC32A1 miRNA 3'UTR clone - MiUTR1H-09531 from Creative biogene
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