Gene Symbol | CDHR5 |
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Entrez Gene | 53841 |
Alt Symbol | MU-PCDH, MUCDHL, MUPCDH |
Species | Human |
Gene Type | protein-coding |
Description | cadherin-related family member 5 |
Other Description | mu-protocadherin|mucin and cadherin-like protein |
Swissprots | Q9HBB5 Q9HBB8 C9J7X1 Q9NXI9 Q9HAU3 Q9NX86 Q9HBB6 Q9HBB7 Q9H746 |
Accessions | AAG16730 AAG16731 EAX02361 EAX02362 EAX02363 EAX02364 EAX02365 EAX02366 EAX02367 Q9HBB8 AA975851 AF258675 AAG16732 AF258676 AAG16733 AF258677 AF258678 AF258679 AF276242 AAG30821 AF301909 AAG33495 AI640262 AK000226 BAA91021 AK000384 BAA91130 AK025012 BAB15052 AK300991 BAG62610 AK308040 AK309157 AW137262 AY358368 AAQ88734 BC038405 AAH38405 BC107063 DA373160 XM_005252987 XP_005253044 XM_005252988 XP_005253045 XM_005252989 XP_005253046 XM_005252990 XP_005253047 XM_006718253 XP_006718316 XM_011520188 XP_011518490 XM_011520189 XP_011518491 XM_011520190 XP_011518492 XM_011520191 XP_011518493 NM_001171968 NP_001165439 NM_021924 NP_068743 NM_031264 NP_112554 NM_017717 NM_031265 |
Function | Acts as a calcium-dependent cell adhesion protein. {ECO:0000250|UniProtKB:Q9JIK1}. |
Subcellular Location | Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Highest expression in kidney, liver, colon and small intestine. In kidney, expressed apically along brush border of proximal convoluted tubule but not in cortical collecting ducts. Isoform 1 is expressed primarily in adult small intestine and colon. Isoform 2 is highly expressed in fetal liver. {ECO:0000269|PubMed:12167596}. |
μ-protocadherin CRISPR/Cas9 KO Plasmid (h) - sc-406015 from Santa Cruz Biotechnology
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μ-protocadherin HDR Plasmid (h) - sc-406015-HDR from Santa Cruz Biotechnology
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μ-protocadherin Double Nickase Plasmid (h) - sc-406015-NIC from Santa Cruz Biotechnology
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μ-protocadherin Double Nickase Plasmid (h2) - sc-406015-NIC-2 from Santa Cruz Biotechnology
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μ-protocadherin CRISPR Activation Plasmid (h) - sc-406015-ACT from Santa Cruz Biotechnology
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μ-protocadherin CRISPR Activation Plasmid (h2) - sc-406015-ACT-2 from Santa Cruz Biotechnology
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μ-protocadherin Lentiviral Activation Particles (h) - sc-406015-LAC from Santa Cruz Biotechnology
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μ-protocadherin Lentiviral Activation Particles (h2) - sc-406015-LAC-2 from Santa Cruz Biotechnology
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μ-protocadherin siRNA (h) - sc-72286 from Santa Cruz Biotechnology
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μ-protocadherin shRNA Plasmid (h) - sc-72286-SH from Santa Cruz Biotechnology
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μ-protocadherin shRNA (h) Lentiviral Particles - sc-72286-V from Santa Cruz Biotechnology
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MUCDHL RNAi - H00053841-R01 from Novus Biologicals
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MUCDHL RNAi - H00053841-R03 from Novus Biologicals
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MUCDHL RNAi - H00053841-R04 from Novus Biologicals
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MISSION® esiRNA - EHU134871 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5832 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5832 from Sigma-Aldrich
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CDHR5 siRNA (Human) - CRH9993 from Cohesion Biosciences
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MUCDHL RNAi - H00053841-R02 from Novus Biologicals
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CDHR5 - MBS8201534 from MyBioSource
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μ-protocadherin CRISPR/Cas9 KO Plasmid (h2) - sc-406015-KO-2 from Santa Cruz Biotechnology
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μ-protocadherin HDR Plasmid (h2) - sc-406015-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human CDHR5 (NM_021924.4) - SHH260429 from Creative biogene
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Human CDHR5 siRNA - orb270495 from Biorbyt
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CDHR5 shRNA Plasmid (Human) - CHH9993 from Cohesion Biosciences
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