| Gene Symbol |
Ugt2b
|
| Entrez Gene |
24862
|
| Alt Symbol |
Ugt2b2
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
UDP glycosyltransferase 2 family, polypeptide B
|
| Other Description |
3-hydroxyandrogen specific|3-hydroxyandrogen-specific UDPGT|Androsterone UDP-glucuronosyltransferase|RLUG23|UDP glucuronosyltransferase|UDP-glucuronosyltransferase 2B2|UDPGT 2B2|UDPGTr-4
|
| Swissprots |
P08541
|
| Accessions |
AAA42314 AAM51149 P08541 BC089792 AAH89792 DQ351215 ABC71921 EX489691 FQ102904 FQ240959 X03478 CAA27198 NM_031533 NP_113721
|
| Function |
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. 2B2 acts on various endogenous steroids, especially etiocholanolone and androsterone.
|
| Subcellular Location |
Microsome membrane {ECO:0000305}; Single- pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
|
| Top Pathways |
Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450
|