Gene Symbol | GH1 |
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Entrez Gene | 2688 |
Alt Symbol | GH, GH-N, GHN, IGHD1B, hGH-N |
Species | Human |
Gene Type | protein-coding |
Description | growth hormone 1 |
Other Description | pituitary growth hormone|somatotropin |
Swissprots | Q9UNL5 Q16631 A6NEF6 Q9UMJ7 Q14405 Q9HBZ1 P01241 Q5EB53 |
Accessions | AAA52549 AAA98618 ABZ88711 ABZ88712 ABZ88713 ABZ88714 ABZ88715 CAA01057 CAA23779 EAW94233 EAW94239 EAW94251 EAW94261 P01241 A00469 CAA00065 AF110644 AAD48584 AF185611 AAG09699 AV749353 AV753220 AY613431 AAT11508 AY613432 AAT11509 BC062475 AAH62475 BC075012 AAH75012 BC075013 AAH75013 BC090045 AAH90045 CD108592 M14398 AAA52554 V00519 CAA23778 XM_011524612 XP_011522914 NM_000515 NP_000506 NM_022559 NP_072053 NM_022560 NP_072054 NM_022561 NM_022562 |
Function | Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. |
Subcellular Location | Secreted. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, PI3K-Akt signaling pathway, Neuroactive ligand-receptor interaction |
GH-1 CRISPR/Cas9 KO Plasmid (h) - sc-401112 from Santa Cruz Biotechnology
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GH-1 HDR Plasmid (h) - sc-401112-HDR from Santa Cruz Biotechnology
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GH-1 Double Nickase Plasmid (h) - sc-401112-NIC from Santa Cruz Biotechnology
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GH-1 Double Nickase Plasmid (h2) - sc-401112-NIC-2 from Santa Cruz Biotechnology
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GH CRISPR Activation Plasmid (h) - sc-401112-ACT from Santa Cruz Biotechnology
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GH-1 CRISPR Activation Plasmid (h2) - sc-401112-ACT-2 from Santa Cruz Biotechnology
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GH-1 Lentiviral Activation Particles (h) - sc-401112-LAC from Santa Cruz Biotechnology
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GH-1 Lentiviral Activation Particles (h2) - sc-401112-LAC-2 from Santa Cruz Biotechnology
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GH-1 siRNA (h) - sc-43803 from Santa Cruz Biotechnology
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GH-1 shRNA Plasmid (h) - sc-43803-SH from Santa Cruz Biotechnology
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GH-1 shRNA (h) Lentiviral Particles - sc-43803-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU218081 from Sigma-Aldrich
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MISSION® esiRNA - EHU128241 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9271 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9271 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01346 from Sigma-Aldrich
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GH1 siRNA (Human) - CRH1791 from Cohesion Biosciences
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GH1 - MBS8210312 from MyBioSource
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shRNA set against Human GH1 (NM_000515.3) - SHH300938 from Creative biogene
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shRNA set against Human GH1(NM_022560.2) - SHH083693 from Creative biogene
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shRNA set against Human GH1(NM_022561.2) - SHH083729 from Creative biogene
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shRNA set against Human GH1(NM_022562.2) - SHH083747 from Creative biogene
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shRNA set against Human GH1(NM_022559.2) - SHH083765 from Creative biogene
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Human GH1 siRNA - orb262293 from Biorbyt
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GH1 shRNA Plasmid (Human) - CHH1791 from Cohesion Biosciences
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