Gene Symbol | AHCY |
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Entrez Gene | 191 |
Alt Symbol | SAHH, adoHcyase |
Species | Human |
Gene Type | protein-coding |
Description | adenosylhomocysteinase |
Other Description | S-adenosyl-L-homocysteine hydrolase|S-adenosylhomocysteine hydrolase |
Swissprots | E1P5P2 F5H737 B3KUN3 Q96A36 P23526 A8K307 |
Accessions | EAW76279 EAW76280 EAW76281 P23526 AK097610 BAG53495 AK290422 BAF83111 AK300014 BAG61829 AK309204 AK316180 BAH14551 BC010018 AAH10018 BC011606 AAH11606 BC114924 AAI14925 BE785593 BT006697 AAP35343 DB043400 DC301059 DC413105 DQ890569 ABM92186 DQ891701 ABM82627 DQ893730 ABM84656 DQ895397 ABM86323 HG511319 M61831 AAA51681 M61832 AAA51682 XM_005260316 XP_005260373 XM_005260317 XP_005260374 XM_011528656 XP_011526958 XM_011528657 XP_011526959 XM_011528658 XP_011526960 XM_011528659 XP_011526961 XM_011528660 XP_011526962 NM_000687 NP_000678 NM_001161766 NP_001155238 |
Function | Adenosylhomocysteine is a competitive inhibitor of S- adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine. {ECO:0000269|PubMed:12590576}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Top Pathways | Cysteine and methionine metabolism |
Human S adenosylhomocysteine hydrolase full length protein - ab99326 from Abcam
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Human S adenosylhomocysteine hydrolase full length protein - ab124607 from Abcam
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Human S adenosylhomocysteine hydrolase full length protein - ab196391 from Abcam
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SAHH / AHCY Antibody Blocking Peptide - LS-E832 from LifeSpan Bioscience
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SAHH / AHCY Antibody Blocking Peptide - LS-E7052 from LifeSpan Bioscience
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SAHH / AHCY Antibody Blocking Peptide - LS-E7053 from LifeSpan Bioscience
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SAHH / AHCY Antibody Blocking Peptide - LS-E18562 from LifeSpan Bioscience
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SAHH / AHCY Antibody Blocking Peptide - LS-E18561 from LifeSpan Bioscience
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Adenosylhomocysteinase/AHCY Recombinant Protein - H00000191-P01 from Novus Biologicals
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Recombinant Human Adenosylhomocysteinase/AHCY Protein - NBP1-45271 from Novus Biologicals
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Adenosylhomocysteinase/AHCY Peptide - P1223 from Novus Biologicals
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Adenosylhomocysteinase/AHCY Peptide - P1222 from Novus Biologicals
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AHCY-Antibody-N-term-Blocking-peptide - BP11201a from Abgent, a WuXi AppTec company
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S-adenosylhomocysteine-hydrolase-ACHY-Antibody-C-term-Blocking-peptide - BP2733b from Abgent, a WuXi AppTec company
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S-adenosylhomocysteine-hydrolase-ACHY-Antibody-N-term-Blocking-peptide - BP2733a from Abgent, a WuXi AppTec company
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Recombinant Human Adenosylhomocysteinease/AHCY, CF - 6466-AH-010 from R&D Systems
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AHCY Protein (OPPA02254) - OPPA02254 from Aviva Systems Biology
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Human AHCY protein - orb246290 from Biorbyt
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Human AHCY protein - orb90018 from Biorbyt
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AHCY Blocking Peptide - 33R-8359 from Fitzgerald
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AHCY protein (His tag) - 80R-1369 from Fitzgerald
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AdoHcyase / AHCY (1-432, His-tag) - AR09543PU-L from Acris Antibodies
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AdoHcyase / AHCY (1-432, His-tag) - AR09543PU-N from Acris Antibodies
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AdoHcyase (AHCY) - H00000191-P01-10 from Acris Antibodies
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AdoHcyase (AHCY) - H00000191-P01-25 from Acris Antibodies
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