Gene Symbol | SLC6A5 |
---|---|
Entrez Gene | 9152 |
Alt Symbol | GLYT-2, GLYT2, HKPX3, NET1 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 6 (neurotransmitter transporter), member 5 |
Other Description | glycine transporter 2|sodium- and chloride-dependent glycine transporter 2|solute carrier family 6 (neurotransmitter transporter, glycine), member 5 |
Swissprots | Q9BX77 Q9Y345 Q4VAM7 O95288 |
Accessions | EAW68330 Q9Y345 AA625644 AF085412 AAC95145 AF117999 AAK12641 AF142501 AAD27892 AF352733 AAK29670 BC096319 AAH96319 BC096320 AAH96320 BC096321 AAH96321 BC096322 AAH96322 XM_005253225 XP_005253282 XM_011520473 XP_011518775 NM_004211 NP_004202 |
Function | Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May be responsible for the termination of neurotransmission at strychnine-sensitive glycinergic synapses. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in medulla, and to a lesser extent in spinal cord and cerebellum. |
GlyT2 CRISPR/Cas9 KO Plasmid (h) - sc-403077 from Santa Cruz Biotechnology
|
||||||||
GlyT2 HDR Plasmid (h) - sc-403077-HDR from Santa Cruz Biotechnology
|
||||||||
GlyT2 Double Nickase Plasmid (h) - sc-403077-NIC from Santa Cruz Biotechnology
|
||||||||
GlyT2 Double Nickase Plasmid (h2) - sc-403077-NIC-2 from Santa Cruz Biotechnology
|
||||||||
GlyT2 CRISPR Activation Plasmid (h) - sc-403077-ACT from Santa Cruz Biotechnology
|
||||||||
GlyT2 CRISPR Activation Plasmid (h2) - sc-403077-ACT-2 from Santa Cruz Biotechnology
|
||||||||
GlyT2 Lentiviral Activation Particles (h) - sc-403077-LAC from Santa Cruz Biotechnology
|
||||||||
GlyT2 Lentiviral Activation Particles (h2) - sc-403077-LAC-2 from Santa Cruz Biotechnology
|
||||||||
GlyT2 siRNA (h) - sc-41976 from Santa Cruz Biotechnology
|
||||||||
GlyT2 shRNA Plasmid (h) - sc-41976-SH from Santa Cruz Biotechnology
|
||||||||
GlyT2 shRNA (h) Lentiviral Particles - sc-41976-V from Santa Cruz Biotechnology
|
||||||||
GlyT2/SLC6A5 RNAi - H00009152-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU154621 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN2199 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2199 from Sigma-Aldrich
|
||||||||
SLC6A5 siRNA (Human) - CRH6057 from Cohesion Biosciences
|
||||||||
SLC6A5 - MBS8201896 from MyBioSource
|
||||||||
GlyT2 CRISPR/Cas9 KO Plasmid (h2) - sc-403077-KO-2 from Santa Cruz Biotechnology
|
||||||||
GlyT2 HDR Plasmid (h2) - sc-403077-HDR-2 from Santa Cruz Biotechnology
|
||||||||
shRNA set against Human SLC6A5 (NM_004211.3) - SHH411972 from Creative biogene
|
||||||||
Human SLC6A5 siRNA - orb266559 from Biorbyt
|
||||||||
SLC6A5 shRNA Plasmid (Human) - CHH6057 from Cohesion Biosciences
|
||||||||
SLC6A5 miRNA 3'UTR clone - MiUTR1H-09594 from Creative biogene
|