Gene Symbol | ASCC1 |
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Entrez Gene | 51008 |
Alt Symbol | ASC1p50, CGI-18, p50 |
Species | Human |
Gene Type | protein-coding |
Description | activating signal cointegrator 1 complex subunit 1 |
Other Description | ASC-1 complex subunit P50|trip4 complex subunit p50 |
Swissprots | Q96EI8 Q5SW06 Q8N9N2 Q9Y307 Q5SW07 |
Accessions | EAW54444 EAW54445 EAW54446 EAW54447 Q8N9N2 AA805081 AF132952 AAD27727 AK023436 BAG51193 AK093971 AK094170 BAC04299 AK096409 BAG53282 AK124364 AK298302 BAH12754 AL359339 AW006945 AY013290 AAG45476 BC012291 AAH12291 CD706699 DA297980 DA582532 DA942671 DA951859 DC361917 HQ448286 ADQ32766 XM_006717873 XP_006717936 XM_011539840 XP_011538142 XM_011539841 XP_011538143 XM_011539842 XP_011538144 XM_011539843 XP_011538145 XM_011539844 XP_011538146 NM_001198798 NP_001185727 NM_001198799 NP_001185728 NM_001198800 NP_001185729 NR_045564 NM_015947 |
Function | Enhances NF-kappa-B, SRF and AP1 transactivation. In cells responding to gastrin-activated paracrine signals, it is involved in the induction of SERPINB2 expression by gastrin. {ECO:0000269|PubMed:19074642}. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Ubiquitous. |
ASCC1 CRISPR/Cas9 KO Plasmid (h) - sc-417767 from Santa Cruz Biotechnology
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ASCC1 HDR Plasmid (h) - sc-417767-HDR from Santa Cruz Biotechnology
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ASCC1 Double Nickase Plasmid (h) - sc-417767-NIC from Santa Cruz Biotechnology
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ASCC1 Double Nickase Plasmid (h2) - sc-417767-NIC-2 from Santa Cruz Biotechnology
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ASCC1 CRISPR Activation Plasmid (h) - sc-417767-ACT from Santa Cruz Biotechnology
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ASCC1 CRISPR Activation Plasmid (h2) - sc-417767-ACT-2 from Santa Cruz Biotechnology
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ASCC1 Lentiviral Activation Particles (h) - sc-417767-LAC from Santa Cruz Biotechnology
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ASCC1 Lentiviral Activation Particles (h2) - sc-417767-LAC-2 from Santa Cruz Biotechnology
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ASCC1 siRNA (h) - sc-90650 from Santa Cruz Biotechnology
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ASCC1 shRNA Plasmid (h) - sc-90650-SH from Santa Cruz Biotechnology
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ASCC1 shRNA (h) Lentiviral Particles - sc-90650-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU071211 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3585 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3585 from Sigma-Aldrich
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ASCC1 siRNA (Human) - CRH9449 from Cohesion Biosciences
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ASCC1 RNAi - H00051008-R01 from Novus Biologicals
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ASCC1 - MBS8202010 from MyBioSource
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ASCC1 shRNA Plasmid (Human) - CHH9449 from Cohesion Biosciences
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