Gene Symbol | GINS4 |
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Entrez Gene | 84296 |
Alt Symbol | SLD5 |
Species | Human |
Gene Type | protein-coding |
Description | GINS complex subunit 4 (Sld5 homolog) |
Other Description | DNA replication complex GINS protein SLD5|SLD5 homolog |
Swissprots | B2R8H5 Q9BRT9 Q8N648 D3DSY0 |
Accessions | EAW63256 EAW63257 Q9BRT9 AK095334 BAG53029 AK299207 BAG61247 AK313373 BAG36172 BC005995 AAH05995 BC027454 AAH27454 DC376966 XM_005273659 XP_005273716 NM_032336 NP_115712 |
Function | The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS4 is important for GINS complex assembly. GINS complex seems to bind preferentially to single-stranded DNA. {ECO:0000269|PubMed:17417653}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
SLD5 CRISPR/Cas9 KO Plasmid (h) - sc-417246 from Santa Cruz Biotechnology
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SLD5 HDR Plasmid (h) - sc-417246-HDR from Santa Cruz Biotechnology
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SLD5 Double Nickase Plasmid (h) - sc-417246-NIC from Santa Cruz Biotechnology
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SLD5 Double Nickase Plasmid (h2) - sc-417246-NIC-2 from Santa Cruz Biotechnology
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SLD5 CRISPR Activation Plasmid (h) - sc-417246-ACT from Santa Cruz Biotechnology
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SLD5 CRISPR Activation Plasmid (h2) - sc-417246-ACT-2 from Santa Cruz Biotechnology
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SLD5 Lentiviral Activation Particles (h) - sc-417246-LAC from Santa Cruz Biotechnology
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SLD5 Lentiviral Activation Particles (h2) - sc-417246-LAC-2 from Santa Cruz Biotechnology
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SLD5 siRNA (h) - sc-77602 from Santa Cruz Biotechnology
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SLD5 shRNA Plasmid (h) - sc-77602-SH from Santa Cruz Biotechnology
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SLD5 shRNA (h) Lentiviral Particles - sc-77602-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU041391 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9294 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9294 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01986 from Sigma-Aldrich
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GINS4 siRNA (Human) - CRJ3420 from Cohesion Biosciences
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GINS4 - MBS8224512 from MyBioSource
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shRNA set against Human GINS4 (NM_032336.2) - SHH301182 from Creative biogene
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GINS4 shRNA Plasmid (Human) - CHJ3420 from Cohesion Biosciences
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GINS4 miRNA 3'UTR clone - MiUTR4H-TG03817 from Creative biogene
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