Gene Symbol |
ABRA
|
Entrez Gene |
137735
|
Alt Symbol |
STARS
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
actin-binding Rho activating protein
|
Other Description |
actin-binding Rho-activating protein|striated muscle activator of Rho-dependent signaling
|
Swissprots |
Q8N0Z2
|
Accessions |
EAW91907 Q8N0Z2 AF503617 AAM27268 AK056976 AK092694 BAC03948 AL832152 AL833422 AM393063 CAL37941 BC105103 AAI05104 BC105105 AAI05106 NM_139166 NP_631905
|
Function |
Acts as an activator of serum response factor (SRF)- dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling. {ECO:0000250|UniProtKB:Q8BUZ1}.
|
Subcellular Location |
Cytoplasm, myofibril, sarcomere {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Localized to the I-band of the sarcomere and to a lesser extent to the sarcomeric structure between Z-lines. {ECO:0000250}.
|