Gene Symbol | ACSM5 |
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Entrez Gene | 54988 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | acyl-CoA synthetase medium-chain family member 5 |
Other Description | acyl-coenzyme A synthetase ACSM5, mitochondrial |
Swissprots | Q96CX8 Q96AV1 Q9NWV3 Q6NUN0 |
Accessions | EAW50317 EAW50318 EAW50319 Q6NUN0 AK000588 BAA91273 AV648626 AV653851 AV696798 BC013753 AAH13753 BC016703 AAH16703 BC068516 AAH68516 BX505437 XM_006721055 XP_006721118 XM_006721056 XP_006721119 NM_017888 NP_060358 |
Function | Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4- unsaturated acids (in vitro) (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion matrix {ECO:0000250}. |
Tissue Specificity | Detected in kidney and liver. {ECO:0000269|PubMed:12654705}. |
Top Pathways | Butanoate metabolism |
ACSM5 CRISPR/Cas9 KO Plasmid (h) - sc-412406 from Santa Cruz Biotechnology
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ACSM5 HDR Plasmid (h) - sc-412406-HDR from Santa Cruz Biotechnology
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ACSM5 Double Nickase Plasmid (h) - sc-412406-NIC from Santa Cruz Biotechnology
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ACSM5 Double Nickase Plasmid (h2) - sc-412406-NIC-2 from Santa Cruz Biotechnology
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ACSM5 CRISPR Activation Plasmid (h) - sc-412406-ACT from Santa Cruz Biotechnology
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ACSM5 CRISPR Activation Plasmid (h2) - sc-412406-ACT-2 from Santa Cruz Biotechnology
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ACSM5 Lentiviral Activation Particles (h) - sc-412406-LAC from Santa Cruz Biotechnology
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ACSM5 Lentiviral Activation Particles (h2) - sc-412406-LAC-2 from Santa Cruz Biotechnology
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ACSM5 siRNA (h) - sc-93223 from Santa Cruz Biotechnology
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ACSM5 shRNA Plasmid (h) - sc-93223-SH from Santa Cruz Biotechnology
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ACSM5 shRNA (h) Lentiviral Particles - sc-93223-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU067951 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2762 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2762 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03983 from Sigma-Aldrich
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ACSM5 siRNA (Human) - CRJ0385 from Cohesion Biosciences
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ACSM5 - MBS8233594 from MyBioSource
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shRNA set against Human ACSM5 (NM_017888.2) - SHH230834 from Creative biogene
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ACSM5 shRNA Plasmid (Human) - CHJ0385 from Cohesion Biosciences
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ACSM5 miRNA 3'UTR clone - MiUTR1H-03704 from Creative biogene
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