Gene Symbol | SRPK3 |
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Entrez Gene | 26576 |
Alt Symbol | MSSK-1, MSSK1, STK23 |
Species | Human |
Gene Type | protein-coding |
Description | SRSF protein kinase 3 |
Other Description | SFRS protein kinase 3|SR-protein-specific kinase 3|muscle-specific serine kinase 1|serine arginine rich protein-specific kinase 3|serine/arginine-rich protein-specific kinase 3|serine/threonine kinase 23|serine/threonine-protein kinase 23|serine/threonine-protein kinase SRPK3 |
Swissprots | Q4F970 Q13583 Q9UM62 Q9UPE1 Q562F5 |
Accessions | EAW72812 EAW72813 EAW72814 Q9UPE1 AF027406 AAD01848 AK301749 BAG63211 AK314828 BC092416 AAH92416 BC117124 AAI17125 DQ099381 AAZ13757 U82808 AAD00539 NM_001170760 NP_001164231 NM_001170761 NP_001164232 NM_014370 NP_055185 |
Function | Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development (By similarity). {ECO:0000250}. |
Tissue Specificity | Exclusively expressed in skeletal and heart muscle. {ECO:0000269|PubMed:11063724}. |
SRPK3 CRISPR/Cas9 KO Plasmid (h) - sc-405831 from Santa Cruz Biotechnology
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SRPK3 HDR Plasmid (h) - sc-405831-HDR from Santa Cruz Biotechnology
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SRPK3 Double Nickase Plasmid (h) - sc-405831-NIC from Santa Cruz Biotechnology
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SRPK3 Double Nickase Plasmid (h2) - sc-405831-NIC-2 from Santa Cruz Biotechnology
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SRPK3 CRISPR Activation Plasmid (h) - sc-405831-ACT from Santa Cruz Biotechnology
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SRPK3 CRISPR Activation Plasmid (h2) - sc-405831-ACT-2 from Santa Cruz Biotechnology
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SRPK3 Lentiviral Activation Particles (h) - sc-405831-LAC from Santa Cruz Biotechnology
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SRPK3 Lentiviral Activation Particles (h2) - sc-405831-LAC-2 from Santa Cruz Biotechnology
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SRPK3 siRNA (h) - sc-39233 from Santa Cruz Biotechnology
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SRPK3 shRNA Plasmid (h) - sc-39233-SH from Santa Cruz Biotechnology
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SRPK3 shRNA (h) Lentiviral Particles - sc-39233-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU036091 from Sigma-Aldrich
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MISSION® siRNA - SIHK2126 from Sigma-Aldrich
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MISSION® siRNA - SIHK2128 from Sigma-Aldrich
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MISSION® siRNA - SIHK2127 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2397 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2397 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00943 from Sigma-Aldrich
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SRPK3 siRNA (Human) - CRH8862 from Cohesion Biosciences
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SRPK3/STK23 RNAi - H00026576-R02 from Novus Biologicals
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SRPK3 - MBS8221507 from MyBioSource
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shRNA set against Human SRPK3 (NM_014370.3) - SHH418012 from Creative biogene
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Human SRPK3 siRNA - orb269364 from Biorbyt
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SRPK3 shRNA Plasmid (Human) - CHH8862 from Cohesion Biosciences
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SRPK3 miRNA 3'UTR clone - MiUTR3H-16166 from Creative biogene
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