Gene Symbol | ATP5G3 |
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Entrez Gene | 518 |
Alt Symbol | P3 |
Species | Human |
Gene Type | protein-coding |
Description | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) |
Other Description | ATP synthase F(0) complex subunit C3, mitochondrial|ATP synthase lipid-binding protein, mitochondrial|ATP synthase proteolipid P3|ATP synthase proton-transporting mitochondrial F(0) complex subunit C3|ATP synthase subunit 9|ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)|ATP synthase, mitochondrial, C subunit-3|ATPase protein 9|ATPase subunit C |
Swissprots | D3DPF0 B2R4Z0 Q4ZFX7 P48201 |
Accessions | AAX88970 EAX11105 EAX11106 EAX11107 EAX11108 P48201 AK125917 AK311999 BAG34937 AW025164 BC106881 AAI06882 BF210704 BI756002 BI765737 BQ054164 CA424417 CR407601 CAG28411 EU832770 ACE87781 GQ129314 ACT64448 U09813 AAA78807 NM_001002258 NP_001002258 NM_001190329 NP_001177258 NM_001689 NP_001680 |
Function | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element. |
Subcellular Location | Mitochondrion membrane; Multi-pass membrane protein. |
Top Pathways | Alzheimer's disease, Huntington's disease, Oxidative phosphorylation |
ATP5G3 CRISPR/Cas9 KO Plasmid (h) - sc-403317 from Santa Cruz Biotechnology
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ATP5G3 HDR Plasmid (h) - sc-403317-HDR from Santa Cruz Biotechnology
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ATP5G3 Double Nickase Plasmid (h) - sc-403317-NIC from Santa Cruz Biotechnology
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ATP5G3 Double Nickase Plasmid (h2) - sc-403317-NIC-2 from Santa Cruz Biotechnology
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ATP5G3 CRISPR Activation Plasmid (h) - sc-403317-ACT from Santa Cruz Biotechnology
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ATP5G3 CRISPR Activation Plasmid (h2) - sc-403317-ACT-2 from Santa Cruz Biotechnology
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ATP5G3 Lentiviral Activation Particles (h) - sc-403317-LAC from Santa Cruz Biotechnology
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ATP5G3 Lentiviral Activation Particles (h2) - sc-403317-LAC-2 from Santa Cruz Biotechnology
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ATP5G3 siRNA (h) - sc-94597 from Santa Cruz Biotechnology
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ATP5G3 shRNA Plasmid (h) - sc-94597-SH from Santa Cruz Biotechnology
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ATP5G3 shRNA (h) Lentiviral Particles - sc-94597-V from Santa Cruz Biotechnology
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ATP5G3 RNAi - H00000518-R01 from Novus Biologicals
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ATP5G3 RNAi - H00000518-R03 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN3703 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3703 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10833 from Sigma-Aldrich
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ATP5G3 siRNA (Human) - CRH0359 from Cohesion Biosciences
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ATP5G3 RNAi - H00000518-R02 from Novus Biologicals
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ATP5G3 - MBS8225703 from MyBioSource
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shRNA set against Human ATP5G3 (NM_001689.4) - SHH242830 from Creative biogene
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shRNA set against Human ATP5G3(NM_001002258.4) - SHG082511 from Creative biogene
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Human ATP5G3 siRNA - orb260861 from Biorbyt
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ATP5G3 shRNA Plasmid (Human) - CHH0359 from Cohesion Biosciences
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ATP5G3 miRNA 3'UTR clone - MiUTR1H-00698 from Creative biogene
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ATP5G3 miRNA 3'UTR clone - MiUTR4H-TG10648 from Creative biogene
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