| Gene Symbol |
AGPAT4
|
| Entrez Gene |
56895
|
| Alt Symbol |
1-AGPAT4, LPAAT-delta, dJ473J16.2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
1-acylglycerol-3-phosphate O-acyltransferase 4
|
| Other Description |
1-AGP acyltransferase 4|1-AGPAT 4|1-acyl-sn-glycerol-3-phosphate acyltransferase delta|1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)|lysophosphatidic acid acyltransferase delta|lysophosphatidic acid acyltransferase-delta (LPAAT-delta)
|
| Swissprots |
Q9NRZ5 B4DSF9 Q5TEF0
|
| Accessions |
CAC38597 EAW47577 EAW47578 EAW47579 EAW47580 EAW47581 EAW47582 EAW47583 Q9NRZ5 AF156776 AAF80338 AJ227890 AJ227891 AJ420473 AK074208 AK295025 BAG58081 AK295548 BAG58454 AK295826 BAG58643 AK297636 BAG60008 AK299721 BAG61621 AL122123 AL832128 AY358506 AAQ88870 BC013410 AAH13410 BC020209 AAH20209 BQ072907 CR627395 CAH10489 HQ447676 ADQ32161 XM_005267053 XP_005267110 XM_005267054 XP_005267111 XM_006715512 XP_006715575 XM_006715514 XP_006715577 XM_006715515 XP_006715578 NM_020133 NP_064518 NM_001012733 NM_001012734
|
| Function |
Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. {ECO:0000250}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Widely expressed with highest levels in skeletal muscle, followed by heart, liver, prostate and thymus. {ECO:0000269|PubMed:21173190}.
|
| Top Pathways |
Glycerolipid metabolism, Glycerophospholipid metabolism
|
![Western Blot: Agpat4 Overexpression Lysate (Adult Normal) [NBL1-07385] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Agpat4.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3647_Agpat4%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-07385-img0002.jpg)