Gene Symbol | ORM2 |
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Entrez Gene | 5005 |
Alt Symbol | AGP-B, AGP-B', AGP2 |
Species | Human |
Gene Type | protein-coding |
Description | orosomucoid 2 |
Other Description | AGP 2|OMD 2|alpha-1-acid glycoprotein 2|alpha-1-acid glycoprotein, type 2|orosomucoid-2 |
Swissprots | Q16571 Q5T538 Q6IB74 P19652 B2R5L2 |
Accessions | AAA51549 CAA29873 CAA29874 EAW87417 P19652 AK303760 BAG64727 AK312226 BAG35159 AV661485 BC015964 AAH15964 BC056239 AAH56239 CR456930 CAG33211 HQ448739 ADQ33217 NM_000608 NP_000599 |
Function | Functions as transport protein in the blood stream. Binds various hydrophobic ligands in the interior of its beta- barrel domain. Also binds synthetic drugs and influences their distribution and availability. Appears to function in modulating the activity of the immune system during the acute-phase reaction. {ECO:0000269|PubMed:21349832}. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed by the liver and secreted in plasma. |
AGP-2 CRISPR/Cas9 KO Plasmid (h) - sc-417370 from Santa Cruz Biotechnology
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AGP-2 HDR Plasmid (h) - sc-417370-HDR from Santa Cruz Biotechnology
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AGP-2 Double Nickase Plasmid (h) - sc-417370-NIC from Santa Cruz Biotechnology
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AGP-2 Double Nickase Plasmid (h2) - sc-417370-NIC-2 from Santa Cruz Biotechnology
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AGP-2 CRISPR Activation Plasmid (h) - sc-417370-ACT from Santa Cruz Biotechnology
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AGP-2 CRISPR Activation Plasmid (h2) - sc-417370-ACT-2 from Santa Cruz Biotechnology
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AGP-2 Lentiviral Activation Particles (h) - sc-417370-LAC from Santa Cruz Biotechnology
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AGP-2 Lentiviral Activation Particles (h2) - sc-417370-LAC-2 from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU224581 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16150 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16150 from Sigma-Aldrich
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ORM2 siRNA (Human) - CRH3323 from Cohesion Biosciences
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Orosomucoid 2 RNAi - H00005005-R01 from Novus Biologicals
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shRNA set against Human Orm2 (NM_000608.2) - SHH368516 from Creative biogene
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shRNA set against Human ORM2(NM_000608.2) - SHR080952 from Creative biogene
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ORM2 shRNA Plasmid (Human) - CHH3323 from Cohesion Biosciences
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ORM2 miRNA 3'UTR clone - MiUTR1H-07390 from Creative biogene
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