Gene Symbol | IPMK |
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Entrez Gene | 253430 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | inositol polyphosphate multikinase |
Other Description | inositol 1,3,4,6-tetrakisphosphate 5-kinase |
Swissprots | Q8NFU5 |
Accessions | EAW54161 Q8NFU5 AF432853 AAM97838 AK096839 BAG53373 BC016612 BC065709 AAH65709 BK000580 DAA01362 XM_011539565 XP_011537867 NM_152230 NP_689416 |
Function | Inositol phosphate kinase with a broad substrate specificity. Has a preference for inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) and inositol 1,3,4,6-tetrakisphosphate (Ins(1,3,4,6)P4). {ECO:0000269|PubMed:12027805, ECO:0000269|PubMed:12223481}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:12027805}. |
Tissue Specificity | Ubiquitous, with the highest expression in skeletal muscle, liver, placenta, lung, peripheral blood leukocytes, kidney, spleen and colon. {ECO:0000269|PubMed:12223481}. |
Top Pathways | Inositol phosphate metabolism |
IPMK CRISPR/Cas9 KO Plasmid (h) - sc-404352 from Santa Cruz Biotechnology
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IPMK HDR Plasmid (h) - sc-404352-HDR from Santa Cruz Biotechnology
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IPMK Double Nickase Plasmid (h) - sc-404352-NIC from Santa Cruz Biotechnology
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IPMK Double Nickase Plasmid (h2) - sc-404352-NIC-2 from Santa Cruz Biotechnology
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IPMK CRISPR Activation Plasmid (h) - sc-404352-ACT from Santa Cruz Biotechnology
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IPMK CRISPR Activation Plasmid (h2) - sc-404352-ACT-2 from Santa Cruz Biotechnology
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IPMK Lentiviral Activation Particles (h) - sc-404352-LAC from Santa Cruz Biotechnology
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IPMK Lentiviral Activation Particles (h2) - sc-404352-LAC-2 from Santa Cruz Biotechnology
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IPMK siRNA (h) - sc-90569 from Santa Cruz Biotechnology
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IPMK shRNA Plasmid (h) - sc-90569-SH from Santa Cruz Biotechnology
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IPMK shRNA (h) Lentiviral Particles - sc-90569-V from Santa Cruz Biotechnology
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IPMK RNAi - H00253430-R02 from Novus Biologicals
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MISSION® esiRNA - EHU147751 from Sigma-Aldrich
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MISSION® siRNA - SIHK0972 from Sigma-Aldrich
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MISSION® siRNA - SIHK0970 from Sigma-Aldrich
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MISSION® siRNA - SIHK0971 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10728 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10728 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01309 from Sigma-Aldrich
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IPMK siRNA (Human) - CRJ6641 from Cohesion Biosciences
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IPMK - MBS8241195 from MyBioSource
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shRNA set against Human IPMK (NM_152230.4) - SHH320129 from Creative biogene
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IPMK shRNA Plasmid (Human) - CHJ6641 from Cohesion Biosciences
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IPMK miRNA 3'UTR clone - MiUTR3H-10841 from Creative biogene
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