Gene Symbol |
CTSS
|
Entrez Gene |
1520
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
cathepsin S
|
Other Description |
-
|
Swissprots |
Q6FHS5 D3DV05 P25774 B4DWC9 Q9BUG3 Q5T5I0
|
Accessions |
AAB60643 CCQ77674 EAW53517 EAW53518 EAW53519 P25774 AK024855 AK226095 AK301472 BAG62991 AK314482 BAG37086 BC002642 AAH02642 BQ006623 CR541676 CAG46477 M86553 AAA35655 M90696 AAC37592 S93414 AAB22005 NM_001199739 NP_001186668 NM_004079 NP_004070
|
Function |
Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond- specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.
|
Subcellular Location |
Lysosome.
|
Top Pathways |
Lysosome, Phagosome, Tuberculosis, Antigen processing and presentation
|