Gene Symbol | CTSS |
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Entrez Gene | 1520 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | cathepsin S |
Other Description | - |
Swissprots | Q6FHS5 D3DV05 P25774 B4DWC9 Q9BUG3 Q5T5I0 |
Accessions | AAB60643 CCQ77674 EAW53517 EAW53518 EAW53519 P25774 AK024855 AK226095 AK301472 BAG62991 AK314482 BAG37086 BC002642 AAH02642 BQ006623 CR541676 CAG46477 M86553 AAA35655 M90696 AAC37592 S93414 AAB22005 NM_001199739 NP_001186668 NM_004079 NP_004070 |
Function | Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond- specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N. |
Subcellular Location | Lysosome. |
Top Pathways | Lysosome, Phagosome, Tuberculosis, Antigen processing and presentation |
cathepsin S CRISPR/Cas9 KO Plasmid (h) - sc-417407 from Santa Cruz Biotechnology
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cathepsin S HDR Plasmid (h) - sc-417407-HDR from Santa Cruz Biotechnology
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cathepsin S Double Nickase Plasmid (h) - sc-417407-NIC from Santa Cruz Biotechnology
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cathepsin S Double Nickase Plasmid (h2) - sc-417407-NIC-2 from Santa Cruz Biotechnology
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cathepsin S CRISPR Activation Plasmid (h) - sc-417407-ACT from Santa Cruz Biotechnology
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cathepsin S CRISPR Activation Plasmid (h2) - sc-417407-ACT-2 from Santa Cruz Biotechnology
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cathepsin S Lentiviral Activation Particles (h) - sc-417407-LAC from Santa Cruz Biotechnology
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cathepsin S Lentiviral Activation Particles (h2) - sc-417407-LAC-2 from Santa Cruz Biotechnology
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cathepsin S siRNA (h) - sc-29940 from Santa Cruz Biotechnology
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cathepsin S shRNA Plasmid (h) - sc-29940-SH from Santa Cruz Biotechnology
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cathepsin S shRNA (h) Lentiviral Particles - sc-29940-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU001241 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6759 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6759 from Sigma-Aldrich
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CTSS siRNA (Human) - CRH1074 from Cohesion Biosciences
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CTSS - MBS8219950 from MyBioSource
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shRNA set against Human CTSS (NM_004079.4) - SHH271661 from Creative biogene
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CTSS shRNA Plasmid (Human) - CHH1074 from Cohesion Biosciences
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CTSS miRNA 3'UTR clone - MiUTR4H-TG11019 from Creative biogene
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