Gene Symbol | TRIB2 |
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Entrez Gene | 28951 |
Alt Symbol | C5FW, GS3955, TRB2 |
Species | Human |
Gene Type | protein-coding |
Description | tribbles pseudokinase 2 |
Other Description | tribbles homolog 2 |
Swissprots | D6W510 Q92519 B2R851 |
Accessions | AAY15015 EAX00907 EAX00908 EAX00909 Q92519 AK129973 AK299146 BAH12958 AK313237 BAG36048 AY245544 AAO89231 BC002637 AAH02637 BQ188880 CN293921 D87119 BAA13250 DC379987 NM_021643 NP_067675 NR_027303 |
Function | Interacts with MAPK kinases and regulates activation of MAP kinases. Does not display kinase activity (By similarity). {ECO:0000250|UniProtKB:Q28283, ECO:0000250|UniProtKB:Q96RU8}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=May associate with the cytoskeleton. {ECO:0000250}. |
Tissue Specificity | Highly expressed in peripheral blood leukocytes. {ECO:0000269|PubMed:15299019}. |
TRB-2 CRISPR/Cas9 KO Plasmid (h) - sc-403132 from Santa Cruz Biotechnology
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TRB-2 HDR Plasmid (h) - sc-403132-HDR from Santa Cruz Biotechnology
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TRB-2 Double Nickase Plasmid (h) - sc-403132-NIC from Santa Cruz Biotechnology
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TRB-2 Double Nickase Plasmid (h2) - sc-403132-NIC-2 from Santa Cruz Biotechnology
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TRB-2 CRISPR Activation Plasmid (h) - sc-403132-ACT from Santa Cruz Biotechnology
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TRB-2 CRISPR Activation Plasmid (h2) - sc-403132-ACT-2 from Santa Cruz Biotechnology
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TRB-2 Lentiviral Activation Particles (h) - sc-403132-LAC from Santa Cruz Biotechnology
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TRB-2 Lentiviral Activation Particles (h2) - sc-403132-LAC-2 from Santa Cruz Biotechnology
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TRB-2 siRNA (h) - sc-94644 from Santa Cruz Biotechnology
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TRB-2 shRNA Plasmid (h) - sc-94644-SH from Santa Cruz Biotechnology
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TRB-2 shRNA (h) Lentiviral Particles - sc-94644-V from Santa Cruz Biotechnology
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TRIB2 RNAi - H00028951-R01V from Novus Biologicals
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MISSION® esiRNA - EHU119201 from Sigma-Aldrich
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MISSION® siRNA - SIHK2329 from Sigma-Aldrich
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MISSION® siRNA - SIHK2327 from Sigma-Aldrich
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MISSION® siRNA - SIHK2328 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2476 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2476 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10683 from Sigma-Aldrich
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TRIB2 siRNA (Human) - CRH9121 from Cohesion Biosciences
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TRIB2 RNAi - H00028951-R02 from Novus Biologicals
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TRIB2 - MBS828473 from MyBioSource
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shRNA set against Human TRIB2 (NM_021643.3) - SHH434328 from Creative biogene
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Human TRIB2 siRNA - orb269623 from Biorbyt
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TRIB2 shRNA Plasmid (Human) - CHH9121 from Cohesion Biosciences
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