Gene Symbol |
FAM132B
|
Entrez Gene |
151176
|
Alt Symbol |
C1QTNF15, CTRP15
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
family with sequence similarity 132, member B
|
Other Description |
complement C1q tumor necrosis factor-related protein 15|erythroferrone|myonectin|protein FAM132B
|
Swissprots |
W8S2M9 Q4G0M1
|
Accessions |
AAY24335 Q4G0M1 AI362696 AK094353 BAC04336 BC031951 BC047423 AAH47423 BC063413 H05276 KF984314 AHL84165 NM_152521 NM_001291832 NP_001278761
|
Function |
Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores. Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake (By similarity). {ECO:0000250}.
|
Subcellular Location |
Secreted {ECO:0000250}.
|