Gene Symbol | KCNA3 |
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Entrez Gene | 3738 |
Alt Symbol | HGK5, HLK3, HPCN3, HUKIII, KV1.3, MK3, PCN3 |
Species | Human |
Gene Type | protein-coding |
Description | potassium channel, voltage gated shaker related subfamily A, member 3 |
Other Description | potassium channel 3|potassium voltage-gated channel subfamily A member 3|potassium voltage-gated channel, shaker-related subfamily, member 3|type n potassium channel|voltage-gated K(+) channel HuKIII|voltage-gated potassium channel protein Kv1.3|voltage-gated potassium channel subunit Kv1.3 |
Swissprots | Q5VWN2 P22001 |
Accessions | AAA36425 AAB88073 EAW56457 P22001 AA811374 AK314009 BAG36720 BC035059 AAH35059 BC064595 AAH64595 BM995500 CA438434 DB086905 DQ891663 ABM82589 DQ894850 ABM85776 HG492418 HY035404 L23499 AAC31761 M85217 AAA59457 NM_002232 NP_002223 NR_109845 NR_109846 |
Function | Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein. |
KV1.3 CRISPR/Cas9 KO Plasmid (h) - sc-403814 from Santa Cruz Biotechnology
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KV1.3 HDR Plasmid (h) - sc-403814-HDR from Santa Cruz Biotechnology
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KV1.3 Double Nickase Plasmid (h) - sc-403814-NIC from Santa Cruz Biotechnology
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KV1.3 Double Nickase Plasmid (h2) - sc-403814-NIC-2 from Santa Cruz Biotechnology
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KV1.3 CRISPR Activation Plasmid (h) - sc-403814-ACT from Santa Cruz Biotechnology
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KV1.3 CRISPR Activation Plasmid (h2) - sc-403814-ACT-2 from Santa Cruz Biotechnology
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KV1.3 Lentiviral Activation Particles (h) - sc-403814-LAC from Santa Cruz Biotechnology
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KV1.3 Lentiviral Activation Particles (h2) - sc-403814-LAC-2 from Santa Cruz Biotechnology
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KV1.3 siRNA (h) - sc-42712 from Santa Cruz Biotechnology
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KV1.3 shRNA Plasmid (h) - sc-42712-SH from Santa Cruz Biotechnology
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KV1.3 shRNA (h) Lentiviral Particles - sc-42712-V from Santa Cruz Biotechnology
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Kv1.3 RNAi - H00003738-R01 from Novus Biologicals
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MISSION® esiRNA - EHU154611 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10918 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10918 from Sigma-Aldrich
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KCNA3 siRNA (Human) - CRH2515 from Cohesion Biosciences
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KCNA3, siRNA - MBS8236533 from MyBioSource
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KV1.3 CRISPR/Cas9 KO Plasmid (h2) - sc-403814-KO-2 from Santa Cruz Biotechnology
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KV1.3 HDR Plasmid (h2) - sc-403814-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human KCNA3 (NM_002232.3) - SHH322711 from Creative biogene
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shRNA set against Human KCNA3(NM_002232.3) - SHL188316 from Creative biogene
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Human KCNA3 siRNA - orb263017 from Biorbyt
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KCNA3 shRNA Plasmid (Human) - CHH2515 from Cohesion Biosciences
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KCNA3 miRNA 3'UTR clone - MiUTR1H-05094 from Creative biogene
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