| Gene Symbol |
WDR73
|
| Entrez Gene |
84942
|
| Alt Symbol |
GAMOS, HSPC264
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
WD repeat domain 73
|
| Other Description |
FLJ00296 protein|WD repeat-containing protein 73
|
| Swissprots |
Q9P0B7 Q96JZ1 Q6P4I2
|
| Accessions |
EAX01945 EAX01946 EAX01947 EAX01948 EAX01949 Q6P4I2 AF161382 AAF28942 AK027200 AK027794 BAB55373 AK055578 AK055729 BAG51562 AK090406 BAC03387 AK225068 AK225199 AK295372 BAG58332 BC014115 AAH14115 BC020252 BC050648 AAH50648 BC063392 AAH63392 BM050710 BM875282 BU601517 BX446522 CD514627 CN481562 CX867053 XR_243214 NM_032856 NP_116245 NR_130944 NR_130945 NR_130946 NR_130947
|
| Function |
May play a role in the regulation of microtubule organization and dynamics (PubMed:25466283). {ECO:0000269|PubMed:25466283}.
|
| Subcellular Location |
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:25466283}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:25466283}. Cleavage furrow {ECO:0000269|PubMed:25466283}. Note=During interphase, located in the cytosol. During mitosis, accumulates at the spindle poles and microtubule asters and later in the cleavage furrow. {ECO:0000269|PubMed:25466283}.
|
| Tissue Specificity |
Expressed in kidney and brain. In the kidney, expressed in glomeruli, most probably in podocytes, and in tubules (at protein level). In the brain, expressed in the cerebellum, with high levels in Purkinje cells and their projecting axons, in the deep cerebellar nuclei and in pyramidal neurons of the cerebral cortex (at protein level). In the white matter, mainly present in astrocytes, but not in oligodendrocytes (at protein level). Also highly expressed in endothelial cells of cerebral capillaries (at protein level). {ECO:0000269|PubMed:25466283}.
|