| Gene Symbol |
Mgea5
|
| Entrez Gene |
76055
|
| Alt Symbol |
2810009A20Rik, 4833427O07Rik, 5830447M11Rik, AA408215, Hy5, Ncoat, OGA, mKIAA0679
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
meningioma expressed antigen 5 (hyaluronidase)
|
| Other Description |
N-acetyl-beta-D-glucosaminidase|N-acetyl-beta-glucosaminidase|beta-N-acetylhexosaminidase|beta-hexosaminidase|bifunctional protein NCOAT|meningioma-expressed antigen 5|nuclear cytoplasmic O-GlcNAcase and acetyltransferase|protein O-GlcNAcase
|
| Swissprots |
Q8CFX2 Q8BTT2 Q9CUR7 Q9CSJ4 Q9EQQ9 Q8BK05 Q6ZQ71 Q3ULY7
|
| Accessions |
EDL41968 Q9EQQ9 AF132214 AAG43273 AK012695 BAB28416 AK014781 BAB29550 AK017997 BAB31029 AK040197 AK044963 AK045615 AK054352 BAC35746 AK077613 BAC36900 AK088506 AK088774 BAC40564 AK129188 BAC97998 AK145227 BAE26311 AK169519 BC020093 AAH20093 BC041109 AAH41109 BC054821 AAH54821 BC147259 BC147260 XM_011247390 XP_011245692 NM_023799 NP_076288
|
| Function |
Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4- methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl- beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro) (PubMed:16517082). Does not bind acetyl-CoA and does not have histone acetyltransferase activity. {ECO:0000250|UniProtKB:O60502, ECO:0000269|PubMed:16517082}.
|
| Subcellular Location |
Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
|