Gene Symbol | HDAC11 |
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Entrez Gene | 79885 |
Alt Symbol | HD11 |
Species | Human |
Gene Type | protein-coding |
Description | histone deacetylase 11 |
Other Description | - |
Swissprots | Q96DB2 Q9H6I7 B4DDK1 Q9NTC9 Q9H6X3 |
Accessions | EAW64157 EAW64158 EAW64159 EAW64160 EAW64161 EAW64162 EAW64163 EAW64164 EAW64165 EAW64166 EAW64167 EAW64168 EAW64169 Q96DB2 AK025426 BAB15127 AK025890 BAB15272 AK293223 BAG56762 AK299021 BAG61100 AL137362 CAB70712 AL834223 CAH56375 AM393042 CAL37920 AM393825 CAL38700 AW291816 BC009676 AAH09676 BG708402 CR457341 CAG33622 DB025431 DB556939 XM_005265491 XP_005265548 XM_005265492 XP_005265549 XM_005265493 XP_005265550 XM_006713338 XP_006713401 XM_011534130 XP_011532432 XM_011534131 XP_011532433 XM_011534132 XP_011532434 XM_011534133 XP_011532435 XM_011534134 XP_011532436 XM_011534135 XP_011532437 NM_001136041 NP_001129513 NM_024827 NP_079103 |
Function | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. {ECO:0000269|PubMed:11948178}. |
Subcellular Location | Nucleus. Note=Predominantly nuclear. |
Tissue Specificity | Weakly expressed in most tissues. Strongly expressed in brain, heart, skeletal muscle, kidney and testis. |
Top Pathways | Viral carcinogenesis, Alcoholism |
Active human HDAC11 full length protein - ab80281 from Abcam
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Human HDAC11 full length protein - ab101113 from Abcam
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Human HDAC11 peptide - ab98895 from Abcam
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HDAC11 Antibody Blocking Peptide - LS-E764 from LifeSpan Bioscience
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HDAC11 Antibody Blocking Peptide - LS-E765 from LifeSpan Bioscience
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HDAC11 Antibody Blocking Peptide - LS-E3732 from LifeSpan Bioscience
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HDAC11 Antibody Blocking Peptide - LS-E15746 from LifeSpan Bioscience
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HDAC11 Antibody Blocking Peptide - LS-E15747 from LifeSpan Bioscience
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Recombinant Human HDAC11 Protein - H00079885-P01 from Novus Biologicals
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HDAC11 Peptide - P0229 from Novus Biologicals
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HDAC11 Peptide - P0228 from Novus Biologicals
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HDAC11-Antibody-C-term-Blocking-Peptide - BP1111b from Abgent, a WuXi AppTec company
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HDAC11-Antibody-N-term-Blocking-Peptide - BP1111a from Abgent, a WuXi AppTec company
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HDAC11-Antibody-Center-Blocking-Peptide - BP14943c from Abgent, a WuXi AppTec company
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HDAC 11 Blocking Peptide - 33R-10526 from Fitzgerald
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HDAC11 Blocking Peptide - 33R-10836 from Fitzgerald
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HDAC11 Blocking Peptide - 33R-3701 from Fitzgerald
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HDAC11 Blocking Peptide - 33R-8369 from Fitzgerald
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HDAC11 - H00079885-P01-10 from Acris Antibodies
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HDAC11 - H00079885-P01-25 from Acris Antibodies
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HDAC11 fusion protein - ag2848 from Proteintech Group
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HDAC-11, Active Human Recombinant Protein - GWB-B569A2 from Genway Biotech
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Recombinant Human Histone Deacetylase 11, GST-tagged - HDAC11-1589H from Creative Biomart
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Recombinant Human Histone Deacetylase 11, His-tagged - HDAC11-402H from Creative Biomart
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Recombinant Human Histone deacetylase 11(HDAC11) - CSB-YP010237HU CSB-EP010237HU CSB-BP010237HU CSB-MP010237HU from Cusabio
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