Gene Symbol | MMADHC |
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Entrez Gene | 27249 |
Alt Symbol | C2orf25, CL25022, cblD |
Species | Human |
Gene Type | protein-coding |
Description | methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria |
Other Description | methylmalonic aciduria and homocystinuria type D protein, mitochondrial|protein C2orf25, mitochondrial |
Swissprots | D3DP91 B2R895 O95891 Q9H3L0 |
Accessions | AAY14891 EAX11533 EAX11534 EAX11535 EAX11536 EAX11537 Q9H3L0 AA857973 AF060224 AAG43124 AF131802 AAD20048 AF161510 AAF29125 AK310001 AK313284 BAG36092 BC000932 AAH00932 BC010894 AAH10894 BC022859 AAH22859 BC023995 AAH23995 BG610637 BM456421 BU570084 NM_015702 NP_056517 |
Function | Involved in cobalamin metabolism. {ECO:0000269|PubMed:18385497}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:23270877}. Mitochondrion {ECO:0000269|PubMed:23270877}. |
Tissue Specificity | Widely expressed at high levels. {ECO:0000269|PubMed:18385497}. |
MMADHC CRISPR/Cas9 KO Plasmid (h) - sc-417560 from Santa Cruz Biotechnology
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MMADHC HDR Plasmid (h) - sc-417560-HDR from Santa Cruz Biotechnology
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MMADHC Double Nickase Plasmid (h) - sc-417560-NIC from Santa Cruz Biotechnology
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MMADHC Double Nickase Plasmid (h2) - sc-417560-NIC-2 from Santa Cruz Biotechnology
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MMADHC CRISPR Activation Plasmid (h) - sc-417560-ACT from Santa Cruz Biotechnology
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MMADHC CRISPR Activation Plasmid (h2) - sc-417560-ACT-2 from Santa Cruz Biotechnology
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MMADHC Lentiviral Activation Particles (h) - sc-417560-LAC from Santa Cruz Biotechnology
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MMADHC Lentiviral Activation Particles (h2) - sc-417560-LAC-2 from Santa Cruz Biotechnology
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MMADHC siRNA (h) - sc-94707 from Santa Cruz Biotechnology
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MMADHC shRNA Plasmid (h) - sc-94707-SH from Santa Cruz Biotechnology
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MMADHC shRNA (h) Lentiviral Particles - sc-94707-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU049571 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14418 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14418 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03681 from Sigma-Aldrich
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MMADHC siRNA (Human) - CRH9042 from Cohesion Biosciences
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shRNA set against Human MMADHC (NM_015702.2) - SHH342772 from Creative biogene
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Human MMADHC siRNA - orb269544 from Biorbyt
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MMADHC shRNA Plasmid (Human) - CHH9042 from Cohesion Biosciences
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MMADHC miRNA 3'UTR clone - MiUTR3H-12213 from Creative biogene
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