| Gene Symbol |
Plekhb1
|
| Entrez Gene |
64471
|
| Alt Symbol |
Evt1, Kpl1
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
pleckstrin homology domain containing, family B (evectins) member 1
|
| Other Description |
PH domain-containing family B member 1|evectin-1|pleckstrin homology domain-containing family B member 1
|
| Swissprots |
Q9WU68
|
| Accessions |
EDM18318 EDM18319 EDM18320 EDM18321 EDM18322 EDM18323 Q9WU68 AF081582 AAF21785 AF118562 AAD23762 BC078704 AAH78704 XM_006229787 XP_006229849 XM_006229788 XP_006229850 XM_006229789 XP_006229851 XM_006229791 XP_006229853 XM_008759795 XP_008758017 NM_172033 NP_742030
|
| Function |
Required for proper localization of retinogeniculate projections but not for eye-specific segregation. {ECO:0000250}.
|
| Subcellular Location |
Membrane {ECO:0000269|PubMed:10200314}. Cytoplasm {ECO:0000250}. Note=Membrane-associated. Highly expressed in the outer segments of photoreceptor cells, both in rods and cones. Associated with post-Golgi vesicles. Localizes to the apical juxta-nuclear Golgi region of the cytoplasm (By similarity). {ECO:0000250}.
|
| Tissue Specificity |
Highly expressed in photoreceptor cells, oligodendrocytes and throughout the myelinated parts of the central nervous system. Detected in brain, liver, kidney, spleen and trachea. {ECO:0000269|PubMed:10200314, ECO:0000269|PubMed:10923244}.
|