Gene Symbol | CHRNA4 |
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Entrez Gene | 1137 |
Alt Symbol | BFNC, EBN, EBN1, NACHR, NACHRA4, NACRA4 |
Species | Human |
Gene Type | protein-coding |
Description | cholinergic receptor, nicotinic, alpha 4 (neuronal) |
Other Description | cholinergic receptor, nicotinic, alpha polypeptide 4|neuronal acetylcholine receptor subunit alpha-4|neuronal nicotinic acetylcholine receptor alpha-4 subunit |
Swissprots | Q4VAQ5 Q4JGR7 P43681 Q4VAQ6 |
Accessions | AAV66461 AAW81038 AAW81039 AAY88737 EAW75269 EAW75270 P43681 AK296430 BAG59090 AK314907 BC096290 AAH96290 BC096291 AAH96291 BC096292 AAH96292 BC096293 AAH96293 BM710937 DA530118 L35901 AAA64743 U62433 AAB40111 X87629 CAA60959 X89741 CAA61893 X89742 X89743 X89744 X89745 X89746 Y08421 CAA69698 XM_011528524 XP_011526826 NM_000744 NP_000735 NM_001256573 NP_001243502 NR_046317 |
Function | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions. {ECO:0000269|PubMed:22361591}. |
Subcellular Location | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. |
Top Pathways | Nicotine addiction, Neuroactive ligand-receptor interaction |
Human Nicotinic Acetylcholine Receptor alpha 4 peptide - ab49523 from Abcam
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Human Nicotinic Acetylcholine Receptor alpha 4 peptide - ab102058 from Abcam
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Human Nicotinic Acetylcholine Receptor alpha 4 peptide - ab99319 from Abcam
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Human Nicotinic Acetylcholine Receptor alpha 4 protein fragment - ab152279 from Abcam
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Nicotinic Acetylcholine Receptor alpha 4 peptide - ab123011 from Abcam
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CHRNA4 / NACHR Antibody Blocking Peptide - LS-E10683 from LifeSpan Bioscience
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CHRNA4 / NACHR Antibody Blocking Peptide - LS-E12455 from LifeSpan Bioscience
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CHRNA4 / NACHR Antibody Blocking Peptide - LS-E26676 from LifeSpan Bioscience
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CHRNA4 / NACHR Antibody Blocking Peptide - LS-E26843 from LifeSpan Bioscience
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Recombinant Human Nicotinic Acetylcholine R alpha 4/CHRNA4 Protein - H00001137-Q01 from Novus Biologicals
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AChR alpha 4 (aa29-43) blocking peptide - GTX31078-PEP from GeneTex
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AChR alpha 4 blocking peptide - GTX88811-PEP from GeneTex
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CHRNA4 Blocking Peptide - 33R-2546 from Fitzgerald
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CHRNA4 Blocking Peptide - 33R-1126 from Fitzgerald
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Nicotinic Acetylcholine Receptor alpha 4 Peptide - AC21-1516-P from Abcore
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Nicotinic Acetylcholine Receptor alpha 4 Peptide - AC21-1674-P from Abcore
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Neuronal acetylcholine receptor subunit alpha-4 - H00001137-Q01-10 from Acris Antibodies
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Neuronal acetylcholine receptor subunit alpha-4 - H00001137-Q01-25 from Acris Antibodies
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Neuronal acetylcholine receptor subunit alpha-4 control peptide - BP2144CP from Acris Antibodies
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CHRNA4 Peptide - 46-643P from ProSci
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CHRNA4 Peptide - 42-755P from ProSci
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CHRNA4 fusion protein - Ag16584 from Proteintech Group
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CHRNA4 fusion protein - ag16578 from Proteintech Group
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Recombinant Human CHRNA4, GST-tagged - CHRNA4-11212H from Creative Biomart
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Recombinant Human CHRNA4 - CHRNA4-176H from Creative Biomart
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