Gene Symbol | MMP7 |
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Entrez Gene | 4316 |
Alt Symbol | MMP-7, MPSL1, PUMP-1 |
Species | Human |
Gene Type | protein-coding |
Description | matrix metallopeptidase 7 |
Other Description | matrilysin|matrin|matrix metallopeptidase 7 (matrilysin, uterine)|matrix metalloproteinase 7 (matrilysin, uterine)|matrix metalloproteinase-7|pump-1 protease|uterine matrilysin|uterine metalloproteinase |
Swissprots | Q9BTK9 P09237 |
Accessions | AAC37543 AAV40839 CAY39331 EAW67023 P09237 AI675414 AK222980 BAD96700 AK293359 BAG56875 AK309687 BC003635 AAH03635 BP332706 DQ399600 ABD92799 DQ893132 ABM84058 EU176770 ABW03571 X07819 CAA30678 Z11887 CAA77942 NM_002423 NP_002414 |
Function | Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase. {ECO:0000269|PubMed:2550050}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000305}. |
Top Pathways | Wnt signaling pathway |
MMP-7 CRISPR/Cas9 KO Plasmid (h) - sc-417803 from Santa Cruz Biotechnology
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MMP-7 HDR Plasmid (h) - sc-417803-HDR from Santa Cruz Biotechnology
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MMP-7 Double Nickase Plasmid (h) - sc-417803-NIC from Santa Cruz Biotechnology
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MMP-7 Double Nickase Plasmid (h2) - sc-417803-NIC-2 from Santa Cruz Biotechnology
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MMP-7 CRISPR Activation Plasmid (h) - sc-417803-ACT from Santa Cruz Biotechnology
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MMP-7 CRISPR Activation Plasmid (h2) - sc-417803-ACT-2 from Santa Cruz Biotechnology
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MMP-7 Lentiviral Activation Particles (h) - sc-417803-LAC from Santa Cruz Biotechnology
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MMP-7 Lentiviral Activation Particles (h2) - sc-417803-LAC-2 from Santa Cruz Biotechnology
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MMP-7 siRNA (h) - sc-41553 from Santa Cruz Biotechnology
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MMP-7 shRNA Plasmid (h) - sc-41553-SH from Santa Cruz Biotechnology
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MMP-7 shRNA (h) Lentiviral Particles - sc-41553-V from Santa Cruz Biotechnology
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MMP-7 RNAi - H00004316-R01 from Novus Biologicals
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MISSION® esiRNA - EHU028021 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14438 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14438 from Sigma-Aldrich
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MMP7 siRNA (Human) - CRH2928 from Cohesion Biosciences
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shRNA set against Human MMP7 (NM_002423.3) - SHH343108 from Creative biogene
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shRNA set against Human MMP7(NM_002423.3) - SHH194159 from Creative biogene
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MMP7 shRNA Plasmid (Human) - CHH2928 from Cohesion Biosciences
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MMP7 miRNA 3'UTR clone - MiUTR1H-06362 from Creative biogene
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