Got2

Gene Symbol	Got2
Entrez Gene	25721
Alt Symbol	ASPATA
Species	Rat
Gene Type	protein-coding
Description	glutamic-oxaloacetic transaminase 2, mitochondrial
Other Description	FABP-1|FABPpm|Glutamate oxaloacetate transaminase 2, mitochondrial (aspartate aminotransferase 2)|aspartate aminotransferase, mitochondrial|fatty acid-binding protein|glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)|kynurenine aminotransferase 4|kynurenine aminotransferase IV|kynurenine--oxoglutarate transaminase 4|kynurenine--oxoglutarate transaminase IV|mAspAT|plasma membrane-associated fatty acid-binding protein|transaminase A
Swissprots	Q64551 Q9QV50 P00507
Accessions	CBF96250 CBV09770 EDL87266 P00507 BC061792 AAH61792 CB607680 FM056810 FQ210345 M12709 AAA41267 M18467 AAB54275 NM_013177 NP_037309
Function	Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity). {ECO:0000250}.
Subcellular Location	Mitochondrion matrix {ECO:0000269|PubMed:11962739}. Cell membrane {ECO:0000269|PubMed:11962739}. Note=Located in the mitochondria of liver, pancreas, spleen, heart, pituitary gland and submandibular gland cells. In kidney, located in the mitochondria, on the cell surface of regions with protrusions in distal tubules, on the apical cell surface of protrusions along the microvilli in cortical collecting ducts, in condensing vacuoles, on the cell surface at cell boundaries of adjoining kidney cells and on the cell surface of endothelial cells lining capillaries in the glomerulus. Also located at the cell surface of endothelial cells lining arterioles and on the cell surface of lymphocytes.
Tissue Specificity	Expressed in all tissues tested: liver, pancreas, kidney, heart, spleen, arterioles, and lymphocytes. {ECO:0000269|PubMed:11962739}.
Top Pathways	Cysteine and methionine metabolism, Fat digestion and absorption, Alanine, aspartate and glutamate metabolism, 2-Oxocarboxylic acid metabolism, Carbon metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Aspartate aminotransferase, mitochondrial, Got2, Rat, ELISA Kit - E1612r from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.78-50 ng/mL

Fatty Acid Binding Protein 1, Liver (FABP1), Rat, ELISA Kit - SEB566Ra from ARP American Research Products Category ELISA Kit Prices $742.00 Sizes 96 t Sensitivity 0.27ng/mL Range 0.78 -50ng/mL

Custom Rat FABP-1 ELISA - ELR-FABP1 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

ELISA Kit for Fatty Acid Binding Protein 1, Liver (FABP1) - SEB566Ra from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.27ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA's were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

Rat Aspartate aminotransferase, mitochondrial ELISA Kit - abx256540 from Abbexa Category ELISA Kit Range 0.78 ng/ml - 50 ng/ml

Fatty Acid Binding Protein 1, Liver (FABP1), Rat, ELISA Kit - DL-FABP1-Ra from ARP American Research Products Category ELISA Kit Prices $715.00 Sizes 96 t Range 0.78 -50 ng/mL

Fatty Acid Binding Protein 3, Muscle And Heart (FABP3), Rat, ELISA Kit - DL-FABP3-Ra from ARP American Research Products Category ELISA Kit Prices $715.00 Sizes 96 t Range 0.156-10 ng/mL

Aspartate aminotransferase, mitochondrial, ELISA Kit - MBS288459 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 0.78 ng/mL -50.0 ng/mL.

Custom Rat FABP-1 ELISA Kit - orb159074 from Biorbyt Category ELISA Kit Prices $1,148.00, $1,981.00, $4,284.00 Sizes 96 well, 192 assays, 480 assays

Fatty Acid Binding Protein 1, Liver, FABP1, Rat, ELISA Kit - E-EL-R2435 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Rat Aspartate aminotransferase, mitochondrial ELISA Kit - EKE52790 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Range 0.78-50 ng/mL

Got2 - EKR1130 from Nordic BioSite Sensitivity 0.469ng/ml Range 0.78-50ng/ml

GOT2 ELISA Kit (Rat) (OKEH01160) - OKEH01160 from Aviva Systems Biology Category ELISA Kit Prices $420.00 Sizes 96 wells Sensitivity < 0.34 ng/mL Range 0.78 - 50 ng/mL

Custom Rat FABP-1 ELISA - ELR-FABP1-1 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Rat Got2 ELISA Kit - E074212 from Biobool Category ELISA Kit

Rat Aspartate aminotransferase, mitochondrial ELISA Kit - EK3816 from Signalway Antibody Category ELISA Kit Prices $599.00 Sizes 1x96t Sensitivity less than 3ng/mL Range 7.8-500 ng/mL

Aspartate aminotransferase, ELISA Kit - MBS9427646 from MyBioSource Category ELISA Kit Prices $555.00 Sizes 96 tests Range 0.78-50 ng/mL

Aspartate aminotransferase, mitochondrial, ELISA Kit - MBS764511 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.469ng/ml Range 0.78-50ng/ml

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