| Gene Symbol |
GIMAP1
|
| Entrez Gene |
170575
|
| Alt Symbol |
HIMAP1, IAN2, IMAP1, IMAP38
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
GTPase, IMAP family member 1
|
| Other Description |
GTPase IMAP family member 1|immune-associated nucleotide-binding protein 2|immunity associated protein 1
|
| Swissprots |
B2RCI3 Q8WWP7 Q8NAZ0
|
| Accessions |
EAL24485 EAW54095 Q8WWP7 AJ306287 CAC83740 AK091818 BAC03754 AK315127 BAG37580 AW029312 BC040736 AAH40736 DA817535 NM_130759 NP_570115
|
| Function |
May regulate lymphocyte survival. Required for normal levels of mature T-lymphocytes and mature B-cells (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Golgi apparatus membrane {ECO:0000250}. Golgi apparatus {ECO:0000305}.
|
| Tissue Specificity |
Predominantly expressed in the spleen and to a lesser extent in the lymph nodes. Detected in T-cells. {ECO:0000269|PubMed:11814688, ECO:0000269|PubMed:23454188}.
|
![Western Blot: GIMAP1 Overexpression Lysate (Adult Normal) [NBL1-11071] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GIMAP1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4256_GIMAP1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11071-img0002.jpg)