Gene Symbol | WDR33 |
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Entrez Gene | 55339 |
Alt Symbol | NET14, WDC146 |
Species | Human |
Gene Type | protein-coding |
Description | WD repeat domain 33 |
Other Description | WD repeat-containing protein 33|WD repeat-containing protein WDC146|pre-mRNA 3' end processing protein WDR33 |
Swissprots | Q587J1 Q05DP8 Q9C0J8 Q9NUL1 Q69YF7 Q53FG9 Q6NUQ0 |
Accessions | AAX82033 EAW95342 EAW95343 Q9C0J8 AA142986 AB044749 BAB32435 AI039494 AK002156 BAA92113 AK098003 AK123510 AK223319 BAD97039 AL043051 AL834365 CAH10688 BC005401 AAH05401 BC010283 BC013990 AAH13990 BC068484 AAH68484 BC108671 BC169262 BC169263 BC169264 BM673679 BQ896760 BU597855 DA768238 DB324904 XM_005263697 XP_005263754 XM_011511436 XP_011509738 NM_001006622 NP_001006623 NM_001006623 NP_001006624 NM_018383 NP_060853 |
Function | Essential for both cleavage and polyadenylation of pre- mRNA 3' ends. {ECO:0000269|PubMed:19217410}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:11162572, ECO:0000269|PubMed:19217410}. |
Tissue Specificity | Most highly expressed in testis. {ECO:0000269|PubMed:11162572}. |
Top Pathways | mRNA surveillance pathway |
WDR33 CRISPR/Cas9 KO Plasmid (h) - sc-409284 from Santa Cruz Biotechnology
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WDR33 HDR Plasmid (h) - sc-409284-HDR from Santa Cruz Biotechnology
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WDR33 Double Nickase Plasmid (h) - sc-409284-NIC from Santa Cruz Biotechnology
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WDR33 Double Nickase Plasmid (h2) - sc-409284-NIC-2 from Santa Cruz Biotechnology
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WDR33 CRISPR Activation Plasmid (h) - sc-409284-ACT from Santa Cruz Biotechnology
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WDR33 CRISPR Activation Plasmid (h2) - sc-409284-ACT-2 from Santa Cruz Biotechnology
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WDR33 Lentiviral Activation Particles (h) - sc-409284-LAC from Santa Cruz Biotechnology
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WDR33 Lentiviral Activation Particles (h2) - sc-409284-LAC-2 from Santa Cruz Biotechnology
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WDR33 siRNA (h) - sc-94735 from Santa Cruz Biotechnology
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WDR33 shRNA Plasmid (h) - sc-94735-SH from Santa Cruz Biotechnology
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WDR33 shRNA (h) Lentiviral Particles - sc-94735-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU118901 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22818 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22818 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11623 from Sigma-Aldrich
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WDR33 siRNA (Human) - CRJ0670 from Cohesion Biosciences
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WDR33 - MBS8209986 from MyBioSource
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shRNA set against Human Wdr33 (NM_018383.4) - SHH446072 from Creative biogene
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Human WDR33 siRNA - orb271171 from Biorbyt
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WDR33 shRNA Plasmid (Human) - CHJ0670 from Cohesion Biosciences
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