| Gene Symbol |
CCPG1
|
| Entrez Gene |
9236
|
| Alt Symbol |
CPR8
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cell cycle progression 1
|
| Other Description |
cell cycle progression protein 1|cell cycle progression restoration protein 8
|
| Swissprots |
Q9BY53 O14712 Q8IYV8 Q9ULG6 Q9HA17 A8K9T0 A0PJH3 Q05DG4 Q5U5S7
|
| Accessions |
EAW77481 EAW77482 EAW77483 EAW77484 EAW77485 EAW77486 Q9ULG6 AA740595 AB033080 BAA86568 AF011794 AAB69314 AF212228 AAK14914 AK022459 BAB14042 AK292795 BAF85484 AL705964 BC015203 AAH15203 BC027621 BC029398 AAH29398 BC034914 AAH34914 BC039871 AAH39871 BC042826 DA670725 DA720583 DB084778 JF432363 ADZ15580 NM_001204450 NP_001191379 NM_001204451 NP_001191380 NM_004748 NP_004739 NM_020739 NP_065790
|
| Function |
Acts as an assembly platform for Rho protein signaling complexes. Limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability and its transforming activity. Does not inhibit activity of MCF2L toward CDC42, or activity of MCF2 toward either RHOA or CDC42 (By similarity). May be involved in cell cycle regulation. {ECO:0000250, ECO:0000269|PubMed:9383053}.
|
| Subcellular Location |
Cytoplasmic granule membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
|
![Western Blot: CPR8 Overexpression Lysate (Native) [NBP2-07831] - CPR8 Overexpression Lysate (Native) Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CCPG1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4056_CPR8-Overexpression-Lysate-(Native)-Western-Blot-NBP2-07831-img0002.jpg)
![Western Blot: CPR8 Overexpression Lysate (Native) [NBP2-06619] - CPR8 Overexpression Lysate (Native) Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CCPG1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2090_CPR8-Overexpression-Lysate-(Native)-Western-Blot-NBP2-06619-img0002.jpg)