Gene Symbol | LRRC38 |
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Entrez Gene | 126755 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | leucine rich repeat containing 38 |
Other Description | BK channel auxiliary gamma subunit LRRC38|BK channel auxilliary gamma subunit LRRC38|leucine-rich repeat-containing protein 38 |
Swissprots | Q5VT99 Q96B32 |
Accessions | EAW51689 Q5VT99 BC016048 AAH16048 XM_006710336 XP_006710399 XR_946542 NM_001010847 NP_001010847 |
Function | Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Modulates gating properties by producing a marked shift in the BK channel's voltage dependence of activation in the hyperpolarizing direction, and in the absence of calcium. {ECO:0000269|PubMed:22547800}. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
Tissue Specificity | Mainly expressed in adrenal gland, thymus and skeletal muscle. {ECO:0000269|PubMed:22547800}. |
LRRC38 CRISPR/Cas9 KO Plasmid (h) - sc-417648 from Santa Cruz Biotechnology
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LRRC38 HDR Plasmid (h) - sc-417648-HDR from Santa Cruz Biotechnology
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LRRC38 Double Nickase Plasmid (h) - sc-417648-NIC from Santa Cruz Biotechnology
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LRRC38 Double Nickase Plasmid (h2) - sc-417648-NIC-2 from Santa Cruz Biotechnology
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LRRC38 CRISPR Activation Plasmid (h) - sc-417648-ACT from Santa Cruz Biotechnology
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LRRC38 CRISPR Activation Plasmid (h2) - sc-417648-ACT-2 from Santa Cruz Biotechnology
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LRRC38 Lentiviral Activation Particles (h) - sc-417648-LAC from Santa Cruz Biotechnology
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LRRC38 Lentiviral Activation Particles (h2) - sc-417648-LAC-2 from Santa Cruz Biotechnology
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LRRC38 siRNA (h) - sc-88308 from Santa Cruz Biotechnology
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LRRC38 shRNA Plasmid (h) - sc-88308-SH from Santa Cruz Biotechnology
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LRRC38 shRNA (h) Lentiviral Particles - sc-88308-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU155901 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12735 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12735 from Sigma-Aldrich
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LRRC38 siRNA (Human) - CRJ4882 from Cohesion Biosciences
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shRNA set against Human LRRC38 (NM_001010847.1) - SHH334483 from Creative biogene
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Human LRRC38 siRNA - orb275383 from Biorbyt
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LRRC38 shRNA Plasmid (Human) - CHJ4882 from Cohesion Biosciences
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